86770-80-1Relevant articles and documents
AN UNEXPECTED β-ELIMINATION FROM 3,3-DIFLUOROCYCLOBUTANECARBONITRILE
Hoz, S.,Aurbach, D.,Avivi, C.
, p. 1639 - 1640 (1983)
3,3-Difluorocyclobutanecarbonitrile (2) reacts with bases to give β rather than γ-elimination, the latter being the prevailing reaction mode in similar systems.
IMIDAZO[1,2-A]PYRIDINES AS SOLUBLE GUANYLATE CYCLASE STIMULATORS FOR THE TREATMENT OF CARDIOVASCULAR DISEASES
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, (2017/03/21)
The present application relates to novel substituted imidazo[1,2-a]pyridine-3-carboxamides, to processes for preparation thereof, to the use thereof, alone or in combinations, for treatment and/or prophylaxis of diseases, and to the use thereof for production of medicaments for treatment and/or prophylaxis of diseases, especially for treatment and/or prophylaxis of cardiovascular disorders.
9-AMINOMETHYL SUBSTITUTED TETRACYCLINE COMPOUNDS
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Page/Page column, (2014/07/08)
The present invention relates to 9-aminomethyl substituted tetracycline compounds represented by formula (I), or pharmaceutically acceptable salt, prodrug, solvate or isomer thereof, as well as a method for preparing these compounds and a pharmaceutical composition comprising the same. The present invention relates also to a use of these compounds in the preparation of a medicament for the treatment and/or prophylaxis of tetracycline drug-sensitive disease. wherein, R2a, R2b, R3, R4a, R4b, R5, R6a, R6b, R7, R8, R9a, R9b, R10, R11, R12, R13a and R13b are each independently as defined in the description.