86813-46-9

Basic information

• Product Name: 2-NITRO-5-(1-PIPERAZINYL)BENZALDEHYDEHYDROCHLORIDE
• Synonyms: 2-NITRO-5-(1-PIPERAZINYL)BENZALDEHYDEHYDROCHLORIDE
• CAS NO: 86813-46-9
• Molecular Formula: C₁₁H₁₃N₃O₃*ClH
• Molecular Weight: 0
• Mol File: 86813-46-9.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-NITRO-5-(1-PIPERAZINYL)BENZALDEHYDEHYDROCHLORIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-NITRO-5-(1-PIPERAZINYL)BENZALDEHYDEHYDROCHLORIDE(86813-46-9)
• EPA Substance Registry System: 2-NITRO-5-(1-PIPERAZINYL)BENZALDEHYDEHYDROCHLORIDE(86813-46-9)

Safety Data

• Hazardous Substances Data: 86813-46-9(Hazardous Substances Data)

Upstream product

• 110-85-0 piperazine 
• 13796-06-0 2-nitro-5-chlorobenzaldehyde dimethyl acetal 

Downstream Products

• 81840-07-5 1-(3,4-dimethoxybenzoyl)-4-(3-formyl-4-nitrophenyl)piperazine 
• 81840-05-3 2-nitro-5-piperazinylcinnamic acid 
• 119198-32-2 6-<4-(3,4-dimethoxybenzoyl)-1-piperazinyl>-1H,3H-quinazoline-2,4-dione hydrochloride 
• 119198-28-6 6-<4-(3,4-dimethoxybenzoyl)-1-piperazinyl>-1,4-dihydro-2H-3,1-benzoxazin-2-one hydrochloride 
• 119198-36-6 6-<4-(3,4-dimethoxybenzoyl)-1-piperazinyl>-1,3-dimethyl-1H,3H-quinazoline-2,4-dione 
• 119198-39-9 6-<4-(3,4-dimethoxybenzoyl)-1-piperazinyl>3,4-dihydro-1H-2,1,3-benzothiadiazine-2,2-dioxide 
• 119198-35-5 6-<4-(3,4-dimethoxybenzoyl)-1-piperazinyl>-3-methyl-1H,3H-quinazoline-2,4-dione 
• 119198-41-3 6-<4-(3,4-dimethoxybenzoyl)-1-piperazinyl>-3,4-dihydro-3-methyl-1H-quinazoline-2-thione 
• 119198-40-2 6-[4-(3,4-Dimethoxy-benzoyl)-piperazin-1-yl]-3-methyl-3,4-dihydro-1H-quinazolin-2-one 
• 119198-29-7 5-<4-(3,4-dimethoxybenzoyl)-1-piperazinyl>-2-nitrobenzoic acid 
• 119198-38-8 4-<4-amino-3-(N-metylaminomethyl)phenyl>-1-(3,4-dimethoxybenzoyl)piperazine 
• 119198-37-7 1-(3,4-dimetoxybenzoyl)-4-<3-(N-methylaminomethyl)-4-nitrophenyl>piperazine 
• 119198-24-2 4-(4-amino-3-hydroxymethylphenyl)-1-(3,4-dimethoxybenzoyl)piperazine 
• 119198-30-0 methyl 2-amino-5-<4-(3,4-dimethoxybenzoyl)-1-piperazinyl>benzoate 

Relevant articles and documents

Studies on new platelet aggregation inhibitors 1. Synthesis of 7-nitro-3,4-dihydroquinoline-2(1H)-one derivatives

A series of 6-cyclic aliphatic amino-7-nitro-3,4-dihydroquinoline-2(1H)-ones were prepared and tested for platelet aggregation inhibitory effect, cardiotonic activity and chronotropic activity. These compounds appeared to show selective inhibitory activity against platelet aggregation. Among them, 6-(4-ethoxycarbonylpiperidino)-7-nitro-3,4-dihydroquinoline-2(1H)-one (22f) showed the most potent inhibitory activity and high selectivity. A divergent synthetic route to 6-cyclic aliphatic amino-7-nitro-3,4-dihydroquinoline-2(1H)-one derivatives has also been investigated.

Piperazinylcarbostyril compounds

A piperazinylcarbostyril compound of the formula (I) STR1 wherein R1 represents a hydrogen atom, a lower alkyl group, a lower alkenyl group, a lower alkynyl group, or a phenyl-lower alkyl group; R2 represents a hydrogen atom or a lower alkoxy group; R3 represents a hydrogen atom, a lower alkanoyl group, a furoyl group, a pyridylcarbonyl group, a lower alkanesulfonyl group, a lower alkoxycarbonyl group, a lower alkoxycarbonyl-lower alkyl group, a phenylsulfonyl group which may be substituted with a lower alkyl group on the benzene ring thereof, a lower alkyl group, a lower alkenyl group, a lower alkynyl group, a phenylcarbonyl group, a phenyl-lower alkyl group or a phenyl-lower alkanoyl group where each of said phenylcarbonyl group, phenyl-lower alkyl group and phenyl-lower alkanoyl group may be substituted with 1 to 3 of a lower alkoxy group, a halogen atom, a lower alkyl group, a cyano group, a nitro group, an amino group, a hydroxy group, a lower alkanoylamino group, a lower alkylthio group and a lower alkanoyloxy group, or with a lower alkylenedioxy group on the benzene ring thereof; and the bonding between the 3- and 4-positions of the carbostyril nucleus is a single bond or a double bond; or its pharmaceutically acceptable salt, useful as a cardiotonic agent.