868367-88-8Relevant articles and documents
Preparation and analysis of oligonucleotides containing the C4′-oxidized abasic site and related mechanistic probes
Kim, Jaeseung,Kreller, Cortney R.,Greenberg, Marc M.
, p. 8122 - 8129 (2005)
The C4′-oxidized abasic site (C4-AP) is produced by a variety of DNA damaging agents. This alkali labile lesion can exist in up to four diastereomeric cyclic forms, in addition to the acyclic ketoaldehyde. Synthetic oligonucleotides containing the lesion