86847-70-3 Usage
Uses
Used in Organic Chemistry:
2,2-DIMETHYL-N-(3-TRIMETHYLSILANYL-PYRIDIN-4-YL)-PROPIONAMIDE is used as a reagent in chemical reactions for its unique structural features, which can facilitate specific transformations and syntheses.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 2,2-DIMETHYL-N-(3-TRIMETHYLSILANYL-PYRIDIN-4-YL)-PROPIONAMIDE is used as a building block in the synthesis of various compounds, potentially contributing to the development of new drugs due to its structural complexity and diversity.
Used in Drug Development:
2,2-DIMETHYL-N-(3-TRIMETHYLSILANYL-PYRIDIN-4-YL)-PROPIONAMIDE may be utilized in drug development for its potential biological activities, which could be harnessed to create novel therapeutic agents. Further research is needed to determine its exact role and efficacy in this context.
Check Digit Verification of cas no
The CAS Registry Mumber 86847-70-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,6,8,4 and 7 respectively; the second part has 2 digits, 7 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 86847-70:
(7*8)+(6*6)+(5*8)+(4*4)+(3*7)+(2*7)+(1*0)=183
183 % 10 = 3
So 86847-70-3 is a valid CAS Registry Number.
InChI:InChI=1/C13H22N2OSi/c1-13(2,3)12(16)15-10-7-8-14-9-11(10)17(4,5)6/h7-9H,1-6H3,(H,14,15,16)
86847-70-3Relevant academic research and scientific papers
Regiospecific Electrophilic Substitution of Aminopyridines: Ortho Lithiation of 2-, 3-, and 4-(Pivaloylamino)pyridines
Turner, James A.
, p. 3401 - 3408 (2007/10/02)
2- and 4-(pivaloylamino)pyridines have been shown to undergo metalation exclusively at C-3 and these smoothly react with a variety of electrophiles to produce 2,3- and 3,4-disubstituted pyridines, respectively.Removal of the pivaloyl protecting group results in overall electrophilic substitution of an aminopyridine.Utilization of this method is exemplified by efficient syntheses of 2- and 4-aminonicotinaldehydes.Minor modifications of the reaction conditions permitted exclusive ortho metalation of 2-(pivaloylamino)pyridines additionally functionalized by chloro, fluoro, or methyl groups.Although the major product from reaction of 3-(pivaloylamino)pyridine by this method was metalation at C-4, the reaction was complicated by substantial quantities of product derived from nucleophilic attack by n-butyllithium on the pyridine nucleus.
