868526-40-3

Upstream product

• 868526-35-6 1-(2-pentyloxyphenyl)-but-3-yn-1-ol 
• 89-95-2 2-methyl-benzyl alcohol 
• 7091-14-7 2-pentyloxybenzaldehyde 
• 628-17-1 amyl iodide 
• 898909-69-8 methyl 8-(tert-butyldimethylsilanyloxy)-8-(2-pentyloxyphenyl)-oct-5-ynoate 
• 868526-37-8 tert-butyldimethyl[1-(2-pentyloxyphenyl)-but-3-ynyloxy]silane 
• 868526-38-9 methyl 8-hydroxy-8-(2-pentyloxyphenyl)-oct-5-ynoate 

Downstream Products

• 868584-77-4 (Z)-8-Hydroxy-8-(2-pentyloxy-phenyl)-oct-5-enoic acid 

Relevant academic research and scientific papers

Synthesis of aromatic analogs of 8(S)-HETE and their biological evaluation as activators of the PPAR nuclear receptors

A new family of 8-HETE analogs has been synthesized as dual PPAR α and γ agonists. A versatile strategy has been developed to allow modulations not only around the aromatic core but also on the side chains of these analogs. The affinity of these compounds

Synthesis of new carbo- and heterocyclic analogues of 8-HETE and evaluation of their activity towards the PPARs

A new class of dual PPARs α and γ agonists was developed. These compounds are structural analogues of the arachidonic acid metabolite, the 8-(S)-HETE. A versatile strategy has been introduced to prepare the target molecules having different carbo- and het