7091-14-7 Usage
Uses
Used in Pharmaceutical Research:
AKOS B014088 is used as a research compound for its potential as an antineoplastic agent, targeting the inhibition of dihydrofolate reductase, which is crucial in the proliferation of cancer cells. This makes it a candidate for the development of treatments for various types of cancer.
Used in Antimicrobial Applications:
AKOS B014088 is utilized as an antimicrobial agent, given its ability to inhibit dihydrofolate reductase, an enzyme also essential for bacterial growth and reproduction. This property positions it as a potential candidate for the development of new antibiotics to combat bacterial infections.
Used in Cancer Treatment Research:
AKOS B014088 is used as a subject of research for its potential role in the treatment of various types of cancer. Its mechanism of action, which involves the inhibition of dihydrofolate reductase, suggests that it could be effective in hindering the growth and spread of cancerous cells.
Used in Bacterial Infection Treatment Research:
AKOS B014088 is also used in research aimed at developing treatments for bacterial infections. Its inhibitory effect on dihydrofolate reductase, an enzyme necessary for bacterial survival, makes it a promising candidate for the creation of new antimicrobial therapies.
Check Digit Verification of cas no
The CAS Registry Mumber 7091-14-7 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 7,0,9 and 1 respectively; the second part has 2 digits, 1 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 7091-14:
(6*7)+(5*0)+(4*9)+(3*1)+(2*1)+(1*4)=87
87 % 10 = 7
So 7091-14-7 is a valid CAS Registry Number.
InChI:InChI=1/C12H16O2/c1-2-3-6-9-14-12-8-5-4-7-11(12)10-13/h4-5,7-8,10H,2-3,6,9H2,1H3
7091-14-7Relevant academic research and scientific papers
Synthesis of aromatic analogs of 8(S)-HETE and their biological evaluation as activators of the PPAR nuclear receptors
Caijo, Frederic,Mosset, Paul,Gree, Rene,Audinot-Bouchez, Valerie,Boutin, Jean,Renard, Pierre,Caignard, Daniel-Henri,Dacquet, Catherine
, p. 2181 - 2196 (2007/10/03)
A new family of 8-HETE analogs has been synthesized as dual PPAR α and γ agonists. A versatile strategy has been developed to allow modulations not only around the aromatic core but also on the side chains of these analogs. The affinity of these compounds
Synthesis of new carbo- and heterocyclic analogues of 8-HETE and evaluation of their activity towards the PPARs
Caijo, Frederic,Mosset, Paul,Gree, Rene,Audinot-Bouchez, Valerie,Boutin, Jean,Renard, Pierre,Caignard, Daniel-Henri,Dacquet, Catherine
, p. 4421 - 4426 (2007/10/03)
A new class of dual PPARs α and γ agonists was developed. These compounds are structural analogues of the arachidonic acid metabolite, the 8-(S)-HETE. A versatile strategy has been introduced to prepare the target molecules having different carbo- and het
Secondary amines
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, (2008/06/13)
Compounds of formula (II): STR1 or salt thereof; wherein R1 is hydrogen or methyl, R2 is hydrogen or methyl, R3 is hydrogen, C1-12 straight or branched alkyl, C3-10 cycloalkyl, phenyl(C1-4)-alkyl or benzyl optionally substituted by C1-4 alkyl, C1-4 alkoxy or halogen; R4 is hydrogen, halogen, hydroxy, C1-4 alkyl or C1-4 alkoxy, R5 is hydrogen or fluorine, R6 is hydrogen or fluorine, R7 is halogen; and n is 1 or 2, have anti-obesity and/or anti-hyperglycaemic activity.
