868614-30-6

Upstream product

• 745052-94-2 ethyl 2-(4-cyclopropylsulfanylphenyl)-2-oxoacetate 
• 868670-98-8 7(S)-iodomethyl-2(1S),3(S)-diphenyl-1,4-dioxaspiro[4,4]nonane 
• 868614-28-2 2-(4-cyclopropylsulfanyl-phenyl)-N-((1R,2R)-2-hydroxy-1-methyl-2-phenyl-ethyl)-N-methyl-acetamide 

Downstream Products

• 868614-29-3 2(R)-(4-cyclopropylsulfanylphenyl)-3-((R)-3-oxocyclopentyl)propionic acid 
• 868614-31-7 2(R)-(4-cyclopropylsulfonylphenyl)-3-((R)-3-oxocyclopentyl)propionic acid 

Relevant academic research and scientific papers

TRICYCLO SUBSTITUTED AMIDES AS GLUCOKINASE MODULATORS

Compounds of Formula (I): (I) or pharmaceutically acceptable salts thereof, are useful in the prophylactic and therapeutic treatment of hyperglycemia and diabetes.

SUBSTITUTED PHENYLACETAMIDES AND THEIR USE AS GLUCOKINASE ACTIVATORS

Compounds of Formula (I) wherein R1 is a cycloalkylsulphonyl group, or pharmaceutically acceptable salts thereof, are useful in the prophylactic and therapeutic treatment of hyperglycemia and diabetes.

FLUORINATION PROCESS OF PROTECTED AMINOTHIAZOLE

A process for the production of fluorinated compound formula (I) comprising fluorination of a protected aminothiazole. Compounds formula (I) are useful in the preparation of activators of glucokinase.

TRI(CYCLO) SUBSTITUTED AMIDE COMPOUNDS

Compounds of Formula (I) or pharmaceutically acceptable salts thereof, are useful in the prophylactic and therapeutic treatment of hyperglycemia and diabetes.