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868736-13-4

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868736-13-4 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 868736-13-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,6,8,7,3 and 6 respectively; the second part has 2 digits, 1 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 868736-13:
(8*8)+(7*6)+(6*8)+(5*7)+(4*3)+(3*6)+(2*1)+(1*3)=224
224 % 10 = 4
So 868736-13-4 is a valid CAS Registry Number.

868736-13-4Relevant articles and documents

Discovery of a potent and selective Axl inhibitor in preclinical model

Inoue, Satoshi,Yamane, Yoshinobu,Tsukamoto, Shuntaro,Azuma, Hiroshi,Nagao, Satoshi,Murai, Norio,Nishibata, Kyoko,Fukushima, Sayo,Ichikawa, Kenji,Nakagawa, Takayuki,Hata Sugi, Naoko,Ito, Daisuke,Kato, Yu,Goto, Aya,Kakiuchi, Dai,Ueno, Takashi,Matsui, Junji,Matsushima, Tomohiro

, (2021/05/04)

Axl and Mer are a members of the TAM (Tyro3-Axl-Mer) family of receptor tyrosine kinases, which, when activated, can promote tumor cell survival, proliferation, migration, invasion, angiogenesis, and tumor-host interactions. Chronic inhibition of Mer lead

SUBSTITUTED PYRAZOLONE COMPOUNDS AND METHODS OF USE

-

, (2014/02/16)

The present invention provides novel substituted pyrazolone compounds, pharmaceutical acceptable salts and formulations thereof useful in modulating the protein tyrosine kinase activity, and in modulating cellular activities such as proliferation, differentiation, apoptosis, migration and invasion. The invention also provides pharmaceutically acceptable compositions comprising such compounds and methods of using the compositions in the treatment of hyperproliferative disorders in mammals, especially humans.

Process for preparing phenoxypyridine derivatives

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Page/Page column 25, (2008/12/08)

A process for preparing a compound represented by the formula (I): comprising reacting a compound represented by the formula (II) or salt thereof: with a compound represented by the formula (III): in the presence of a condensation reagent, wherein R1 represents 1) optionally substituted azetidin-1-yl, 2) optionally substituted pyrrolidin-1-yl, 3) optionally substituted piperidin-1-yl, etc.; R2, R3, R4 and R5 may be the same or different and each represents hydrogen or fluorine; and R6 represents hydrogen or fluorine.

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