868761-04-0Relevant articles and documents
Difluoro(phenylchalcogen)methylation of aldehydes, ketones, and imines with S-, Se-, and Te-containing reagents PhXCF2H (X = S, Se, Te)
Hu, Mingyou,Wang, Fei,Zhao, Yanchuan,He, Zhengbiao,Zhang, Wei,Hu, Jinbo
experimental part, p. 45 - 58 (2012/03/27)
A series of sulfur-, selenium- and tellurium-containing (phenylchalcogen)difluoromethylation reagents PhSCF2H (1a), PhSeCF2H (1b), and PhTeCF2H (1c) were prepared, and their relative reactivity towards aldehydes, ketones,
Lewis acid-catalyzed tri- and difluoromethylation reactions of aldehydes
Mizuta, Satoshi,Shibata, Norio,Ogawa, Shinichi,Fujimoto, Hiroyuki,Nakamura, Shuichi,Toru, Takeshi
, p. 2575 - 2577 (2008/03/27)
The first Lewis acid-catalyzed trifluoromethylation reactions of aldehydes with Me3SiCF3 under TiF4/DMF, Ti(O iPr)4/DMF and Cu(OAc)2/dppp/toluene conditions are described. We have successfu
Synthesis and transformation of [difluoro(phenylseleno)methyl]- trimethylsilane
Qin, Ying-Ying,Qiu, Xiao-Long,Yang, Yan-Yan,Meng, Wei-Dong,Qing, Feng-Ling
, p. 9040 - 9043 (2007/10/03)
A novel and efficient strategy was developed to synthesize [difluoro(phenylseleno)methyl]trimethylsilane (PhSeCF2-TMS, 2), which was further utilized as a nucleophilic difluoromethylating reagent to incorporate the difluoro-(phenylseleno)methyl (PhSeCF2) group into carbonyl compounds in good yields. The resulting PhSeCF2-containing alcohols 3 could be conveniently converted into corresponding difluoromethyl alcohols 4 by a radical deselenylation.
