868944-81-4Relevant academic research and scientific papers
A new, direct, and efficient synthesis of benzonaphthyridin-5-ones
Cailly, Thomas,Fabis, Frédéric,Rault, Sylvain
, p. 5862 - 5867 (2007/10/03)
Microwave-assisted Suzuki cross-coupling reaction of 2-fluorophenylboronic acid with all orthochlorocyanopyridine isomers allowed the rapid syntheses of key intermediates for anionic ring closure, which was performed using potassium hydroxide under microwave irradiation to give benzonaphthyridin-5-ones in high yields.
Synthesis of azaphenanthridines via anionic ring closure
Hansen, Henriette M.,Lysén, Morten,Begtrup, Mikael,Kristensen, Jesper L.
, p. 9955 - 9960 (2007/10/03)
A new and convergent synthesis of azaphenanthridines via an anionic ring closure is reported. Ortho-lithiation/in situ borylation of cyanopyridines produces the corresponding cyanopyridylboronic esters, which undergo a Suzuki-Miyaura cross-coupling to giv
