86927-17-5Relevant academic research and scientific papers
Design, synthesis, antibacterial and antifungal activity of novel spiro-isoxazolyl bis-[5,5']thiazolidin-4-ones and spiro-isoxazolyl thiazolidin-4-one-[5,5']-1,2-4 oxdiazolines
Rajanarendar, Eligeti,Rao, Enugala Kalyan,Shaik, Firoz Pasha,Reddy, Modugu Nagi,Srinivas, Manda
scheme or table, p. 263 - 274 (2010/12/19)
The synthesis of novel isoxazolyl 1,6-dithia-4,9-diazaspiro[4.4]nonane-3,8- diones (4a-h) and isoxazolyl 1-oxa-6-thia-2,4,9-triazaspiro[4.4]non-2-ene-8-ones (5a-h) analogs is described. Reaction of N-1-{3-methyl-5-[(E)-2-aryl-1- ethenyl]-4-isoxazolyl}-2-c
Synthesis of 3-[4-({Methyl-5-[(E)-2-phenyl-1-ethenyl]-4-isoxazolyl}amino)- 1,3-thiazol-2-yl]-2-aryl-1,3-thiazolan-4-ones as potential biodynamic agents
Rajanarendar,Ramesh,Srinivas,Shaik, Firoz Pasha
body text, p. 733 - 742 (2009/10/15)
A series of isoxazolyl thiazolyl thiazolidinones (4a-h) were synthesized starting from isoxazolyl chloroacetamide 1. Compound 1 upon heating with thiourea in ethanol furnished N4-{3-methyl-5-[(E)-2-phenyl-1-ethenyl]-4- isoxazolyl]-1,3-thiazole-2,4-diamine
Synthesis of 2([methyl-5-[(E)-2-aryl-1-ethenyl]-4-isoxazolyl]imino)-1,3- thiazolan-4-ones and their Mannich bases
Rajanarendar,Ramesh,Rao, E. Kalyan,Reddy, A. Siva Rami
experimental part, p. 2555 - 2564 (2009/08/15)
Isoxazolyl chloroacetamides (2) were obtained from 4-amino-3-methyl-5- styrylisoxazoles (1) on reaction with chloroacetyl chloride. Cyclocondensation of 2 with NH4SCN yielded 2([-methyl-5-(E)-2-aryl-1-ethenyl]-4-isoxazolylimino)- 1,3-thiazolan-4-ones(3).
Cycloadditions: Part V - A Novel Observation in the Attempted Synthesis of β-Lactams
Rajanarendar, E.,Janakirama Rao, C.,Krishna Murthy, A.,Kametani, T.
, p. 187 - 188 (2007/10/02)
The interaction of 4-benzalamino-3-methyl-5-styryl isoxazole (2) with chloroacetyl chloride leads to 4-chloroacetamido-3-methyl-5-styrylisoxazole (4) instead of the expected β-lactam (3).Compound (4) has been also prepared through an unambiguous route.A plausible mechanism involving anchimeric assistance from the olefinic bond of the styryl moiety to arrive at the unexpected product has been proposed.
