869348-39-0

Upstream product

• 623-43-8 crotonic acid methyl ester 
• 19790-60-4 3-Benzyloxypropanal 
• 107174-33-4 tert-butyl(((E)-1-methoxybuta-1,3-dien-1-yl)oxy)dimethylsilane 
• 85960-55-0 (S)-(2-phenylmethoxyethyl)oxirane 
• 75-09-2 dichloromethane 
• 292638-85-8 acrylic acid methyl ester 
• 111322-01-1 (R)-1-benzyloxy-hex-5-en-3-ol 

Downstream Products

• 869348-41-4 methyl (R,E)-7-benzyloxy-5-methansulfonyloxy-2-heptenoate 
• 1431291-01-8 methyl 2-{(2S,4S,6S)-6-[2-(benzyloxy)ethyl]-2-phenyl-1,3-dioxan-4-yl}acetate 

Relevant academic research and scientific papers

Synthesis of atorvastatin lactone linker constructs for target fishing

With the aim of connecting atorvastatin lactone 9 to a linker for affinity-based target fishing, a concise route to the pyrrolecarboxylic acid 8 was developed. Key features of the synthesis of the diol-containing side-chain were a catalytic enantioselecti

A highly enantioselective one-pot synthesis of homoallylic alcohols via tandem asymmetric allyl transfer/olefin cross metathesis

A highly enantioselective one-pot synthesis of linear homoallylic alcohols with terminal ester functionality has been achieved. The reactions were controlled by ordered addition of reagents and catalysts, ensuring complete consumption of aldehyde. The synthetic utility of this strategy has been demonstrated in a short synthesis of a low boiling point intermediate for grahamimycin A.

Synthesis of cis- and trans-2,5-disubstituted tetrahydrofurans by a tandem dihydroxylation-SN2 cyclization sequence

(Chemical Equation Presented) Dihydroxylation of δ- and ε-mesyloxy α,β-unsaturated esters proceeds with in situ cyclization to afford 2,5-disubstituted and 2,3,5-trisubstituted tetrahydrofurans.