86938-17-2

Basic information

• Product Name: BOC-GLU-OET DCHA
• Synonyms: BOC-GLU-OET DCHA;Boc-Glu-OEt;Boc-L-Glutamic Acid Ethyl Ester;(S)-4-((tert-Butoxycarbonyl)amino)-5-ethoxy-5-oxopentanoic acid
• CAS NO: 86938-17-2
• Molecular Formula: C₁₂H₂₁NO₆
• Molecular Weight: 275.29824
• Mol File: 86938-17-2.mol
• Article Data: 9

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: BOC-GLU-OET DCHA(CAS DataBase Reference)
• NIST Chemistry Reference: BOC-GLU-OET DCHA(86938-17-2)
• EPA Substance Registry System: BOC-GLU-OET DCHA(86938-17-2)

Safety Data

• Hazardous Substances Data: 86938-17-2(Hazardous Substances Data)

Usage

General Description

BOC-GLU-OET DCHA (tert-Butyl 2-(((2-(((9H-fluoren-9-yl)methoxy)carbonyl)amino)ethyl)carbamoyl)ethylcarbamoyloxy)ethylcarbamate) is a chemical compound used in the synthesis and modification of peptides. It contains a tert-butyl protecting group, as well as a fluorenylmethoxycarbonyl (Fmoc) protecting group, and is designed for use in solid-phase peptide synthesis. BOC-GLU-OET DCHA is used as a coupling reagent to facilitate the formation of peptide bonds, and its structure allows for the selective deprotection and subsequent modification of specific amino acid residues within a peptide sequence. BOC-GLU-OET DCHA is commonly used in the field of medicinal chemistry and drug development for the production of peptide-based pharmaceuticals.

Upstream product

• 64-17-5 ethanol 
• 2419-94-5 Boc-Glu 
• 83173-71-1 2-(S)-tert-butoxycarbonylaminopentanedioic acid 5-benzyl ester 1-ethyl ester 
• 52454-78-1 L-glutamic acid α-ethyl ester 
• 24424-99-5 di-tert-butyl dicarbonate 
• 141-78-6 ethyl acetate 
• 13574-13-5 Boc-Glu(OBzl)-OH 

Downstream Products

• 1336933-34-6 3-[(4S)-4-amino-5-ethoxy-5-oxopentanamido]-5-chloro-2-hydroxybenzene-1-sulfonic acid 
• 1336933-77-7 C₁₈H₂₅ClN₂O₉S 
• 1948-29-4 (S)-2-Amino-4-(carboxymethyl-carbamoyl)-butyric acid 
• 7432-24-8 L-g-Glutamyl-L-phenylalanine 
• 2566-39-4 (S)-2-((S)-4-Amino-4-carboxy-butyrylamino)-4-methyl-pentanoic acid 
• 1116-22-9 γ-L-glutamyl-L-glutamic acid 
• 1116-22-9 (S)-2-((R)-4-amino-4-carboxybutanamido)pentanedioic acid 
• 144978-35-8 (S)-ethyl N-tert-butoxycarbonylpyroglutamate 
• 1221686-75-4 (S)-2-tert-butoxycarbonylamino-4-(3-{3-[4-(pyridin-2-yloxymethyl)-benzyl]-isoxazol-5-yl}-pyridin-2-ylcarbamoyl)-butyric acid ethyl ester 

Relevant articles and documents

PRODUCTION PROCESSES OF S- AND O-DIACYLATED GAMMA-GLUTAMYL-CYSTEAMINE PRODRUGS

Methods are provided for the synthesis of a compound of formula (X). R2 is selected from -H, -C1-C4-alkyl,-C2-C4-alkenyl and C1-C4-aryl; R3 is selected from -C(O)H and

Synthesis of diacylated γ3-glutamyl-cysteamine prodrugs, and in vitro evaluation of their cytotoxicity and intracellular delivery of cysteamine

To overcome the major disadvantages of cysteamine, the only registered treatment for the rare genetic disease cystinosis, nine prodrugs of γ3-glutamyl-cysteamine (4) were synthesized for evaluation. Esterification of the thiol conferred oxidative stabilit

PROPHYLACTIC AGENT OR THERAPEUTIC AGENT FOR DIABETES OR OBESITY

A medicament having an excellent CaSR agonist action which enables the prevention or treatment of diabetes or obesity is provided by a composition comprising the compound represented by general formula (I) as defined, or a salt thereof.