869384-75-8

Upstream product

• 882304-30-5 3-(4-methylsulfanylphenyl)-1-[4-(tert-butyldimethylsilyloxy)-3-methoxyphenyl]prop-2-yn-1-ol 
• 104-95-0 (4-bromophenyl)thioanisole 
• 18162-48-6 tert-butyldimethylsilyl chloride 
• 121-33-5 vanillin 
• 124153-81-7 2-methyl-4-[4-(methylsulfanyl)phenyl]-3-butyn-2-ol 
• 69404-94-0 O-tert-butyldimethylsilylvanillin 
• 56041-85-1 4-ethynylthioanisole 

Downstream Products

• 869384-77-0 3-(4-methylsulfanylphenyl)-1-(4-hydroxy-3-methoxyphenyl)prop-2-yn-1-one 

Relevant academic research and scientific papers

Synthesis and structure-activity relationship studies of 1,3-diarylprop-2-yn-1-ones: Dual inhibitors of cyclooxygenases and lipoxygenases

A group of 1,3-diarylprop-2-yn-1-ones (13, 17, 23, 26 and 27) possessing a C-3 p-SO2Me COX-2 pharmacophore were designed, synthesized and evaluated as potential dual inhibitors of cyclooxygenase-1/2 (COX-1/2) and 5/15-lipoxygenases (5/15-LOX) t

Synthesis and biological evaluation of 1,3-diphenylprop-2-yn-1-ones as dual inhibitors of cyclooxygenases and lipoxygenases

A new class of 1,3-diphenylprop-2-yn-1-ones possessing a p-MeSO2 COX-2 phamacophore on the C-3 phenyl ring was designed for evaluation as dual inhibitors of cyclooxygenase (COX) and lipoxygenase (LOX). Among the group of compounds evaluated, 1-