86953-53-9Relevant academic research and scientific papers
Synthesis of pyrroles via copper-catalyzed coupling of amines with bromoenones
Pan, Yuanjia,Lu, Hongjian,Fang, Yewen,Fang, Xinqiang,Chen, Liqun,Qian, Junlu,Wang, Junhua,Li, Chaozhong
, p. 1242 - 1246 (2007)
The CuI/N,N-dimethylglycine hydrochloride catalyzed reactions of amines with γ-bromo-substituted γ,δ-unsaturated ketones in the presence of K3PO4 and NH4OAc led to the formation of the corresponding polysubstituted pyrrole
Palladium-Catalyzed Carbonylation. A New Synthesis of α-Methylene γ-, δ-, and ε-Lactams and -Lactones Including Bicyclic Lactams of Pyrrolizidine and Indolizidine Skeletons
Mori, Miwako,Washioka, Yumiko,Urayama, Takao,Yoshiura, Kagari,Chiba, Katsumi,Ban, Yoshio
, p. 4058 - 4067 (2007/10/02)
The insertion of carbon monoxide into vinyl halides bearing the secondary amine or alcohol with a catalytic amount of Pd(OAc)2 and PPh3 was realized to give five-, six-, and seven-membered lactams and lactones carrying α-methylene groups in fairly good yields.Bicyclic heterocycles, pyrrolizidine and indolizidine derivatives, were also synthesized from pyrrolidine and piperidine derivatives possessing vinyl halide groups in the side chain at the 2-position of the ring by means of palladium-catalyzed carbonylation.
