86963-81-7

Upstream product

• 86963-80-6 1-Benzyl-2-[3-(2-methyl-[1,3]dioxolan-2-yl)-propyl]-6-propyl-piperidine-2-carbonitrile 
• 86963-79-3 1-Benzyl-6-propyl-piperidine-2-carbonitrile 
• 3695-28-1 5-iodo-2-pentanone ethylene ketal 
• 5978-08-5 1-chloro-4-(1,3-dioxolane)-n-pentane 

Downstream Products

• 86963-75-9 1-Benzyl-5-methyl-2-propyl-1,2,3,4,5,6,7,8-octahydro-quinoline-5-carbonitrile 
• 27766-71-8 (2S,4aR,5R,8aS)-5-Methyl-2-propyl-decahydro-quinoline 
• 27766-71-8 (rac)-(2R,4aS,5R,8aS)-5-methyl-2-propyl-decahydroquinoline 
• 61475-92-1 (2R,4aS,5S,8aR)-1-Benzyl-5-methyl-2-propyl-decahydro-quinoline 
• 61475-92-1 (rac)-(2R,4aS,5R,8aS)-1-benzyl-5-methyl-2-propyl-decahydroquinoline 
• 27766-71-8 (2S,4aR,8aS)-5-Methyl-2-propyl-decahydro-quinoline 
• 86963-75-9 (2R,5R)-1-Benzyl-5-methyl-2-propyl-1,2,3,4,5,6,7,8-octahydro-quinoline-5-carbonitrile 
• 86963-75-9 (2S,5R)-1-Benzyl-5-methyl-2-propyl-1,2,3,4,5,6,7,8-octahydro-quinoline-5-carbonitrile 

Relevant academic research and scientific papers

2-CYANO Δ PIPERIDINES VIII: BIOMIMETIC APPROACH TO THE SYNTHESIS OF THE DECAHYDROQUINOLINE RING SYSTEM OF POISON-DART FROG TOXINS

A biomimetic approach towards the synthesis of pumiliotoxin C has been developed.The key transformation of enamine equivalent 8 to 9 was catalyzed by contact with alumina.Cyclized intermediate 9 was then reduced stereospecifically to the trans decahydroqu