3695-28-1 Usage
Physical state
Clear, colorless liquid
Physical state
This chemical compound exists as a clear, colorless liquid at room temperature, which makes it suitable for use in various chemical reactions and processes.
Odor
Mild, ether-like
Odor
The compound has a mild, ether-like odor, which is characteristic of many organic compounds containing ether functional groups.
Usage
Reagent in organic synthesis and pharmaceutical research
Usage
1,3-Dioxolane, 2-(3-iodopropyl)-2-methylis primarily used as a reagent in organic synthesis and pharmaceutical research. This means it is employed in the synthesis of various organic compounds and in the development of new pharmaceuticals.
Properties
Solvent and reactant in various chemical reactions
Properties
The compound serves as a solvent, which means it can dissolve other substances, and as a reactant in various chemical reactions. This dual role makes it a versatile compound in the field of chemistry.
Hazardous nature
Considered hazardous if not properly managed and safety precautions are not followed
Hazardous nature
It is important to handle 1,3-Dioxolane, 2-(3-iodopropyl)-2-methylwith caution, as it is considered hazardous if not properly managed. This means that safety precautions, such as wearing appropriate personal protective equipment (PPE) and following proper handling procedures, should be followed to minimize the risk of exposure and potential harm.
Check Digit Verification of cas no
The CAS Registry Mumber 3695-28-1 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 3,6,9 and 5 respectively; the second part has 2 digits, 2 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 3695-28:
(6*3)+(5*6)+(4*9)+(3*5)+(2*2)+(1*8)=111
111 % 10 = 1
So 3695-28-1 is a valid CAS Registry Number.
3695-28-1Relevant academic research and scientific papers
Wu,Ahlberg
, p. 463 - 464 (1994)
The title iodide is prepared in 78% yield from corresponding alcohol (derived from ethyl levulinate) by the reaction with triphenylphosphine and iodine in benzene at room temperature.
Sequential One-Pot Vilsmeier-Haack and Organocatalyzed Mannich Cyclizations to Functionalized Benzoindolizidines and Benzoquinolizidines
Outin, Johanne,Quellier, Pauline,Bélanger, Guillaume
, p. 4712 - 4729 (2020/03/30)
The development of new one-pot sequential cyclizations involving a Vilsmeier-Haack reaction followed by an organocatalyzed Mannich reaction is reported. This synthetic strategy gives access to functionalized indolizidines and quinolizidines in one operation from readily synthesized precursors. Yields and diastereoselectivities are good to excellent when formamides are used to trigger the key step, bearing either an electron-rich aryl or a pyrrole as the nucleophilic partner in the first cyclization.
