869663-56-9

Upstream product

• 59997-51-2 trimethylacetylacetonitrile 
• 619-67-0 4-Hydrazinobenzoic acid 
• 24589-77-3 4-hydrazinobenzoic acid hydrochloride 

Downstream Products

• 725686-68-0 methyl 4-(5-amino-3-tert-butyl-1H-pyrazol-1-yl)benzoate 
• 876300-04-8 3-tert-butyl-1-(4-((tert-butyldimethylsilyloxy)methyl)phenyl)-1H-pyrazol-5-amine 
• 1229649-45-9 N-(4-((4-(3-(3-tert-butyl-1-(4-(hydroxymethyl)phenyl)-1H-pyrazol-5-yl)ureido)naphthalen-1-yloxy)methyl)pyridin-2-yl)-2-methoxyacetamide 
• 1337932-37-2 C₃₄H₃₉Cl₂N₇O₆ 
• 1337932-30-5 1-(4-(4-(3-(3-(tert-butyl)-1-(4-(((tert-butyldimethylsilyl)oxy)methyl)phenyl)-1H-pyrazol-5-yl)ureido)-2,3-dichlorophenoxy)pyrimidin-2-yl)-3-methylurea 
• 1337930-88-7 1-(4-(4-(3-(3-tert-butyl-1-(4-(hydroxymethyl)phenyl)-1H-pyrazol-5-yl)ureido)-2,3-dichlorophenoxy)pyrimidin-2-yl)-3-methylurea 
• 1337932-29-2 N-(6-(4-(3-(3-(tert-butyl)-1-(4-(tert-butyldimethylsilyloxymethyl)phenyl)-1H-pyrazol-5-yl)ureido)-2,3-dichlorophenoxy)pyrimidin-4-yl)-4-(dimethylamino)butanamide 
• 1337930-85-4 N-(6-(4-(3-(3-tert-butyl-1-(4-(hydroxymethyl)phenyl)-1H-pyrazol-5-yl)ureido)-2,3-dichlorophenoxy)pyrimidin-4-yl)-4-(dimethylamino)butanamide 
• 1337932-27-0 tert-butyl 2-(4-(4-(3-(3-tert-butyl-1-(4-((tert-butyldimethylsilyloxy)methyl)phenyl)-1H-pyrazol-5-yl)ureido)-2,3-dichlorophenoxy)pyridin-2-ylamino)-2-oxoethyl(methyl)carbamate 
• 1337930-71-8 N-(4-(4-(3-(3-tert-butyl-1-(4-(hydroxymethyl)phenyl)-1H-pyrazol-5-yl)ureido)-2,3-dichlorophenoxy)pyridin-2-yl)-2-(methylamino)acetamide 

Relevant academic research and scientific papers

POLYAROMATIC UREA DERIVATIVES AND THEIR USE IN THE TREATMENT OF MUSCLE DISEASES

The current invention provides urea derivatives, in particular compounds having the core structure heteroaryl-NH-CO-NH-aryl-O- heteroaryl, for use in treating, ameliorating, delaying, curing and/ or preventing a disease or condition associated with muscle cells and/or satellite cells, such as Duchenne muscular dystrophy, Becker muscular dystrophy, cachexia or sarcopenia.

Inhibitors of Hemopoietic Cell Kinase (P59-HCK) and Their Use in the Treatment of Influenza Infection

The present invention relates inter alia to the treatment or prevention of influenza virus infection (including subtypes influenza A virus, influenza B virus, avian strain H5N1, A/H1N1, H3N2 and/or pandemic influenza) using compounds which inhibit the act

DISUBSTITUTED UREAS AS KINASE INHIBITORS

The invention relates to compounds of the formula (I), their use as kinase inhibitors, new pharmaceutical formulations comprising said compounds, said compounds for use in the diagnostic or therapeutic treatment of warm-blooded animals, especially humans,

UREA COMPOUNDS USEFUL IN THE TREATMENT OF CANCER

Pyrazole urea compounds, pharmaceutical compositions which contain them and methods for treating cancer using them.

Three substituted 4-pyrazolylbenzoates: Hydrogen-bonded supramolecular structures in one, two and three dimensions

The molecules of ethyl 4-(5-amino-3-methyl-1H-pyrazol-1-yl)benzoate, C 13H15N3O2, are linked by two independent N - H...-O hydrogen bonds into a chain of edge-fused and alternating R42(8) a

PHENYLACETAMIDES SUITABLE AS PROTEIN KINASE INHIBITORS

The invention relates to compounds of the formula (I) wherein the moieties R1 , R2, R3, R9, R10 and Q and X, Y and Z are as defined in the specification, and salts thereof; as well as their use, methods of use for them and method of their synthesis, and the like. The compounds are protein kinase inhibitors and can, inter alia, be used in the treatment of various proliferative diseases.