869805-82-3Relevant academic research and scientific papers
Preliminary studies of new proteasome inhibitors in the tumor targeting approach: Synthesis and in vitro cytotoxicity
Vivier, Magali,Jarrousse, Anne-Sophie,Bouchon, Bernadette,Galmier, Marie-Josephe,Auzeloux, Philippe,Sauzieres, Jacques,Madelmont, Jean-Claude
, p. 6731 - 6740 (2005)
The proteasome is a multicatalytic protease that plays a critical role in the cell. The control of proteasomes could, thus, provide a weapon for the treatment of cancer. Therefore, we have synthesized six new peptide aldehyde inhibitors of the proteasome
