869985-78-4

Basic information

• Product Name: 12-(phenylsulfonyl)-7-oxo-5,6,7,12-tetrahydroindolo[3,2-d][2]benzazepine-6-carboxylic acid tert-butyl ester
• Synonyms: 12-(phenylsulfonyl)-7-oxo-5,6,7,12-tetrahydroindolo[3,2-d][2]benzazepine-6-carboxylic acid tert-butyl ester
• CAS NO: 869985-78-4
• Molecular Weight: 488.564
• Mol File: 869985-78-4.mol

Chemical Properties

• CAS DataBase Reference: 12-(phenylsulfonyl)-7-oxo-5,6,7,12-tetrahydroindolo[3,2-d][2]benzazepine-6-carboxylic acid tert-butyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 12-(phenylsulfonyl)-7-oxo-5,6,7,12-tetrahydroindolo[3,2-d][2]benzazepine-6-carboxylic acid tert-butyl ester(869985-78-4)
• EPA Substance Registry System: 12-(phenylsulfonyl)-7-oxo-5,6,7,12-tetrahydroindolo[3,2-d][2]benzazepine-6-carboxylic acid tert-butyl ester(869985-78-4)

Safety Data

• Hazardous Substances Data: 869985-78-4(Hazardous Substances Data)

Upstream product

• 278593-17-2 1-(phenylsulfonyl)-1H-indole-3-carboxylic acid 
• 39959-51-8 2-iodobenzylamine 
• 923603-92-3 N-(2-iodobenzyl)-1-(phenylsulfonyl)-1H-indole-3-carboxamide 

Relevant articles and documents

Synthesis of latonduine derivatives via intramolecular Heck?reaction

The synthesis of indole ring-fused benzazepinone series as latonduine derivatives has been developed via an intramolecular Heck reaction. The scope has been enlarged not only to indole moiety but also to pyrrolo and benzo[b]thiophene nuclei. Several derivatives prepared have been evaluated in vitro for their antiproliferative activities on breast cancer cell lines. Some of them showed promising cytotoxic activities.

Synthesis of fused heterocycles with a benzazepinone moiety via intramolecular Heck coupling

The preparation of fused heterocycles with a benzazepinone moiety was realised via an intramolecular Heck coupling reaction either at position 2 or at position 3 of the heterocyclic system. This method allowed the synthesis of the pyrrolo[2,3-c]azepinone