870009-91-9Relevant academic research and scientific papers
Synthesis and antileishmanial activity of novel 2,4,6-trisubstituted pyrimidines and 1,3,5-triazines
Sunduru, Naresh,Nishi,Palne, Shraddha,Chauhan, Prem M.S.,Gupta, Suman
experimental part, p. 2473 - 2481 (2009/09/30)
A series of 2,4,6-trisubstituted pyrimidines and 1,3,5-triazines have been synthesized and screened for their in vitro and in vivo antileishmanial activity against Leishmania donovani. Among all, 14 compounds have shown promising inhibition of 80-100% at
Synthesis of 2-[3,5-substituted pyrazol-1-yl]-4,6-trisubstituted triazine derivatives as antimalarial agents
Katiyar, Sanjay Babu,Srivastava, Kumkum,Puri,Chauhan, Prem M. S.
, p. 4957 - 4960 (2007/10/03)
A series of 22 compounds were synthesized and screened against Plasmodium falciparum NF-54 strain. Of the screened compounds, 6 compounds showed MIC in the range between 1 and 2 μg/mL. These compounds are 32 times more potent than the cycloguanil which wa
