870066-15-2

Basic information

• Product Name: 2-TRIFLUOROMETHYL-3-CYANOPYRIDINE
• Synonyms: 2-TRIFLUOROMETHYL-3-CYANOPYRIDINE;2-(Trifluoromethyl)pyridine-3-carBonitrile;2-(Trifluoromethyl)-3-cyanopyridine, 2-Trifluoromethylnicotinonitrile;3-Cyano-2-(trifluoromethyl)pyridine
• CAS NO: 870066-15-2
• Molecular Formula: C7H3F3N2
• Molecular Weight: 172.1073296
• Product Categories: Pyridines;Heterocyclic Compounds
• Mol File: 870066-15-2.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 208.3oC at 760 mmHg
• Flash Point: >110°C
• Appearance: /
• Density: 1.344
• Vapor Pressure: 0.215mmHg at 25°C
• Refractive Index: 1.4641
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 2-TRIFLUOROMETHYL-3-CYANOPYRIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-TRIFLUOROMETHYL-3-CYANOPYRIDINE(870066-15-2)
• EPA Substance Registry System: 2-TRIFLUOROMETHYL-3-CYANOPYRIDINE(870066-15-2)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36
• WGK Germany: 3
• Hazardous Substances Data: 870066-15-2(Hazardous Substances Data)

Usage

General Description

2-Trifluoromethyl-3-cyanopyridine is a chemical compound with the molecular formula C7H2F3N3. It is a pyridine derivative with a trifluoromethyl substituent at the 2-position and a cyano group at the 3-position. 2-TRIFLUOROMETHYL-3-CYANOPYRIDINE is commonly used as an intermediate in the synthesis of pharmaceuticals and agrochemicals. It is also utilized in the production of dyes, pigments, and other organic compounds. 2-Trifluoromethyl-3-cyanopyridine is known for its high reactivity and is often handled and stored under strict safety measures due to its potential health hazards.

InChI:InChI=1/C7H3F3N2/c8-7(9,10)6-5(4-11)2-1-3-12-6/h1-3H

Upstream product

• 1146961-23-0 5-(dimethylamino)-2-(2,2,2-trifluoroacetyl)penta-2,4-dienenitrile 
• 557-21-1 zinc(II) cyanide 
• 590371-58-7 3-bromo-2-(trifluoromethyl)pyridine 
• 959108-47-5 2-(trifluoromethyl)nicotinamide 

Downstream Products

• 923288-82-8 3-cyano-2-(trifluoromethyl)pyridine 1-oxide 
• 760-41-8 N-(Trifluoracetyl)harnstoff 
• 1056162-06-1 (2-(trifluoromethyl)pyridin-3-yl)methanamine 

Relevant articles and documents

COMBINATION TREATMENTS COMPRISING ADMINISTRATION OF 1H-PYRAZOLO[4,3-B]PYRIDINES

The present invention provides 1H-pyrazolo[4,3-b]pyridin-7-amines of formula (I) as PDE1 inhibitors together with a second compound useful in the treatment of a neurodegenerative disorder and their combined use as a medicament, in particular for the treatment of neurodegenerative and/or cognitive disorders.

COMBINATION TREATMENTS COMPRISING ADMINISTRATION OF 1H-PYRAZOLO[4,3-B]PYRIDINES

The present invention provides 1H-pyrazolo[4,3-b]pyridin-7-amines of formula (I) as PDE1 inhibitors together with a second compound which compound is useful in the treatment of a psychiatric disorder and their combined use as a medicament, in particular for the treatment of psychiatric and/or cognitive disorders.

4,6-DIAMINONICOTINAMIDE COMPOUND

[Problem] The present invention provides a 4,6-diaminonicotinamide compound which is useful as an active ingredient of a pharmaceutical composition, in particular, a pharmaceutical composition for treating diseases caused by undesirable and/or abnormal cytokine signal transduction. [Means for Solution] The present inventors have extensively studied compounds having a JAK3 inhibitory action, and as a result, they have found that a 4,6-diaminonicotinamide compound which is the compound of the present invention has an excellent JAK3 inhibitory action and is useful as an agent for preventing or treating diseases caused by undesirable and/or abnormal cytokine signal transduction, thereby completing the present invention.