870075-26-6Relevant articles and documents
DISCODERMOLIDE ANALOGUES AND METHODS OF THEIR USE
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Page/Page column 29-30, (2009/03/07)
6- and 7-substituted coumarin and related 6- and 7-substituted lH-quinolin-2-one compounds, pharmaceutical compositions containing these compounds, and methods for their pharmaceutical use are disclosed. In certain embodiments, the 7-substituted coumarin
Design, synthesis, and biological evaluation of simplified analogues of (+)-discodermolide. Additional insights on the importance of the diene, the C(7) hydroxyl, and the lactone
Smith III, Amos B.,Xian, Ming
, p. 5229 - 5232 (2007/10/03)
(Chemical Equation Presented) The design, synthesis, and biological evaluation of seven totally synthetic analogues of the antitumor agent (+)-discodermolide are reported. Saturation of the terminal diene system, alteration of the substituents on the lact