870075-29-9

Upstream product

• 853055-22-8 (S)-2-(tert-Butyl-dimethyl-silanyloxy)-3-((2S,3R)-3-methyl-6-oxo-tetrahydro-pyran-2-yl)-propionaldehyde 
• 837383-29-6 (5R,6S)-6-[(S)-2-(tert-Butyl-dimethyl-silanyloxy)-3-(4-methoxy-benzyloxy)-propyl]-5-methyl-5,6-dihydro-pyran-2-one 
• 850211-67-5 (2R,3R,4R,5R,6S)-5-(tert-Butyl-dimethyl-silanyloxy)-3-(4-methoxy-benzyloxy)-2,4,6-trimethyl-7-trityloxy-heptanal 
• 870075-20-0 (5R,6S)-6-[(S)-2-(tert-Butyl-dimethyl-silanyloxy)-3-hydroxy-propyl]-5-methyl-tetrahydro-pyran-2-one 
• 852049-56-0 tert-Butyl-((Z)-(2S,3R,4S)-6-iodo-3-methoxymethoxy-2,4-dimethyl-hept-5-enyloxy)-dimethyl-silane 
• 870075-02-8 tert-Butyl-[(Z)-(1S,2R,3S,4S)-1-((R)-2-iodo-1-methyl-ethyl)-3-(4-methoxy-benzyloxy)-2,4-dimethyl-oct-5-enyloxy]-dimethyl-silane 
• 870075-25-5 (Z)-(2S,3R,4R,5S,6S)-3-(tert-Butyl-dimethyl-silanyloxy)-5-(4-methoxy-benzyloxy)-2,4,6-trimethyl-dec-7-en-1-ol 
• 870075-23-3 tert-Butyl-[(Z)-(1R,2R,3S,4S)-3-(4-methoxy-benzyloxy)-2,4-dimethyl-1-((S)-1-methyl-2-trityloxy-ethyl)-oct-5-enyloxy]-dimethyl-silane 
• 870075-27-7 (5Z,13Z)-(2S,3R,4S,8S,9R,10R,11S,12S)-9-(tert-Butyl-dimethyl-silanyloxy)-11-(4-methoxy-benzyloxy)-3-methoxymethoxy-2,4,6,8,10,12-hexamethyl-hexadeca-5,13-dien-1-ol 
• 870075-26-6 1-[(Z)-(1S,2R,3R,4S,8S,9R,10S)-3,11-Bis-(tert-butyl-dimethyl-silanyloxy)-9-methoxymethoxy-2,4,6,8,10-pentamethyl-1-((Z)-(S)-1-methyl-pent-2-enyl)-undec-6-enyloxymethyl]-4-methoxy-benzene 

Relevant academic research and scientific papers

Design, synthesis, and biological evaluation of simplified analogues of (+)-discodermolide. Additional insights on the importance of the diene, the C(7) hydroxyl, and the lactone

(Chemical Equation Presented) The design, synthesis, and biological evaluation of seven totally synthetic analogues of the antitumor agent (+)-discodermolide are reported. Saturation of the terminal diene system, alteration of the substituents on the lact