870075-27-7

Upstream product

• 850211-67-5 (2R,3R,4R,5R,6S)-5-(tert-Butyl-dimethyl-silanyloxy)-3-(4-methoxy-benzyloxy)-2,4,6-trimethyl-7-trityloxy-heptanal 
• 870075-23-3 tert-Butyl-[(Z)-(1R,2R,3S,4S)-3-(4-methoxy-benzyloxy)-2,4-dimethyl-1-((S)-1-methyl-2-trityloxy-ethyl)-oct-5-enyloxy]-dimethyl-silane 
• 870075-25-5 (Z)-(2S,3R,4R,5S,6S)-3-(tert-Butyl-dimethyl-silanyloxy)-5-(4-methoxy-benzyloxy)-2,4,6-trimethyl-dec-7-en-1-ol 
• 870075-02-8 tert-Butyl-[(Z)-(1S,2R,3S,4S)-1-((R)-2-iodo-1-methyl-ethyl)-3-(4-methoxy-benzyloxy)-2,4-dimethyl-oct-5-enyloxy]-dimethyl-silane 
• 852049-56-0 tert-Butyl-((Z)-(2S,3R,4S)-6-iodo-3-methoxymethoxy-2,4-dimethyl-hept-5-enyloxy)-dimethyl-silane 
• 870075-26-6 1-[(Z)-(1S,2R,3R,4S,8S,9R,10S)-3,11-Bis-(tert-butyl-dimethyl-silanyloxy)-9-methoxymethoxy-2,4,6,8,10-pentamethyl-1-((Z)-(S)-1-methyl-pent-2-enyl)-undec-6-enyloxymethyl]-4-methoxy-benzene 

Downstream Products

• 870075-29-9 (5R,6S)-6-[(3Z,8Z,16Z)-(2S,5S,6S,7S,11S,12R,13R,14S,15S)-2,12-Bis-(tert-butyl-dimethyl-silanyloxy)-14-(4-methoxy-benzyloxy)-6-methoxymethoxy-5,7,9,11,13,15-hexamethyl-nonadeca-3,8,16-trienyl]-5-methyl-tetrahydro-pyran-2-one 

Relevant academic research and scientific papers

DISCODERMOLIDE ANALOGUES AND METHODS OF THEIR USE

6- and 7-substituted coumarin and related 6- and 7-substituted lH-quinolin-2-one compounds, pharmaceutical compositions containing these compounds, and methods for their pharmaceutical use are disclosed. In certain embodiments, the 7-substituted coumarin

Design, synthesis, and biological evaluation of simplified analogues of (+)-discodermolide. Additional insights on the importance of the diene, the C(7) hydroxyl, and the lactone

(Chemical Equation Presented) The design, synthesis, and biological evaluation of seven totally synthetic analogues of the antitumor agent (+)-discodermolide are reported. Saturation of the terminal diene system, alteration of the substituents on the lact