Studies towards the Synthesis of (-)-Pulvomycin: Construction of the C12-C40 Segment by a Stereoselective Aldol Reaction

Article abstract of DOI:10.1055/a-1464-2576

A convergent strategy was developed for the synthesis of the C12 C40 segment of ( )-pulvomycin. Key step was a diastereoselective aldol reaction between a chiral ethyl ketone representing the C24 C40 fragment and a chiral aldehyde representing the C12 C23