870262-27-4

Upstream product

• 1501-05-9 5-oxo-5-phenylvaleric acid 
• 530-62-1 1,1'-carbonyldiimidazole 

Downstream Products

• 603126-57-4 2-phenyl-2-((trimethylsilyl)oxy)cyclopentanone 
• 1384266-60-7 allyl 5-oxo-5-phenylpentanoate 
• 1384266-48-1 (Z)-prop-1-enyl 5-oxo-5-phenylpentanoate 
• 1384266-47-0 (E)-prop-1-enyl 5-oxo-5-phenylpentanoate 
• 40297-30-1 2-Hydroxy-2-phenylcyclopentan-1-one 

Relevant academic research and scientific papers

[Pd(μ-Br)(PtBu3)]2 as a highly active isomerization catalyst: Synthesis of enol esters from allylic esters

The dimeric Pd(I)-complex [Pd(μ-Br)(PtBu3)] 2 was found to be highly active for catalyzing double-bond migration in various substrates such as unsaturated ethers, alcohols, amides, and arenes, under mild conditions. It efficiently mediates the conversion of allylic esters into enol esters, rather than inserting into the allylic C-O bond. The broad applicability of this reaction was demonstrated with the synthesis of 22 functionalized enol esters.

Electroreductive acylation of aromatic ketones with acylimidazoles

The intermolecular reductive coupling of aromatic ketones with acylimidazoles was effected by electroreduction in the presence of chlorotrimethylsilane and gave α-trimethylsiloxy ketones and esters. The best result was obtained using Bu4NPF6 as a supporting electrolyte and a Pb cathode in THF. The α-trimethylsiloxy-containing products were transformed to the corresponding α-hydroxy ketones and esters by treatment with TBAF in THF. This method was also effective for the intramolecular reductive coupling of δ- and ε-keto acylimidazoles.