87029-84-3

Usage

Uses

Used in Pharmaceutical Industry:
5-Amino-2-hydroxybenzonitrile is used as a key intermediate in the synthesis of pharmaceuticals for its ability to contribute to the development of new drugs with therapeutic potential.
Used in Organic Synthesis:
In the field of organic chemistry, 5-Amino-2-hydroxybenzonitrile is employed as a versatile building block for the creation of a wide range of organic compounds, highlighting its utility in chemical research and development.
Used in Drug Manufacturing:
Specifically, 5-Amino-2-hydroxybenzonitrile is used in the manufacturing process of olverembatinib, a drug with specific therapeutic applications, underlining its importance in the pharmaceutical sector for drug production.
Safety Measures:
When working with 5-Amino-2-hydroxybenzonitrile, it is imperative to adhere to safety protocols, including the use of protective clothing and gloves, and to ensure that the work environment is well-ventilated to minimize health risks associated with exposure to this hazardous substance.

InChI:InChI=1/C7H6N2O/c8-4-5-3-6(9)1-2-7(5)10/h1-3,10H,9H2

Upstream product

• 39835-09-1 5-nitro-2-hydroxybenzonitrile 
• 619-24-9 3-nitrobenzonitrile 
• 611-20-1 salicylonitrile 

Downstream Products

• 1249701-97-0 C₉H₉N₃O₂ 
• 554409-17-5 t-butyl {4-hydroxy-3-[4'-(N-methoxy-N-methyl-carboxamido)-4',5'-dihydrothiazol-2'-yl]-phenyl}carbamate 
• 554409-16-4 2-(5-t-butyloxycarbonylamino-2-hydroxyphenyl)-4',5'-dihydrothiazole-4'-carboxylic acid 
• 883455-48-9 (3-cyano-4-hydroxyphenyl)carbamic acid 2-trimethylsilylethyl ester 
• 554409-15-3 5-t-butyloxycarbonylamino-2-hydroxybenzonitrile 

Relevant academic research and scientific papers

Synthesis of functionalized analogs of pyochelin, a siderophore of Pseudomonas aeruginosa and Burkholderia cepacia

Using an improved synthesis of pyochelin, a siderophore common to several pathogenic Pseudomonas species, three functionalized pyochelin analogs were efficiently synthesized starting from appropriate 2-hydroxybenzonitriles.

NOVEL AMIDE COMPOUNDS WITH MCH ANTAGONISTIC EFFECT AND MEDICAMENTS COMPRISING SAID COMPOUNDS

The invention relates to amide compounds of general formula (I), in which the groups and residues A, B, b, W, X, Y, Z, R1, R2 and R3 have the meanings given in claim 1. The invention further relates to medicaments comprising at least one of said amides. Said medicaments are suitable for the treatment of metabolic disorders and/or eating disorders, in particular, obesity, bulimia, anorexia, hyperphagia, and diabetes as a result of the MCH receptor antagonism.

Bacterial siderophores: Synthesis and biological activities of novel pyochelin analogues

The synthesis and biological activities of four pyochelin analogues substituted in different parts of the molecule are reported: 5-NHBoc-pyochelin, 3″N-Boc-pyochelin, 3″-nor-NH-pyochelin and neopyochelin II, the enantiomer of natural pyochelin. All these