870483-28-6

Basic information

• Product Name: {4-tert-butoxycarbonylamino-4-[3-phenyl-1-(quinolin-3-ylcarbamoyl)-propylcarbamoyl]-butyl}-carbamic acid tert-butyl ester
• CAS NO: 870483-28-6
• Molecular Weight: 619.761
• Mol File: 870483-28-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: {4-tert-butoxycarbonylamino-4-[3-phenyl-1-(quinolin-3-ylcarbamoyl)-propylcarbamoyl]-butyl}-carbamic acid tert-butyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: {4-tert-butoxycarbonylamino-4-[3-phenyl-1-(quinolin-3-ylcarbamoyl)-propylcarbamoyl]-butyl}-carbamic acid tert-butyl ester(870483-28-6)
• EPA Substance Registry System: {4-tert-butoxycarbonylamino-4-[3-phenyl-1-(quinolin-3-ylcarbamoyl)-propylcarbamoyl]-butyl}-carbamic acid tert-butyl ester(870483-28-6)

Safety Data

• Hazardous Substances Data: 870483-28-6(Hazardous Substances Data)

Upstream product

• 57133-29-6 (S)-2,5-bis((tert-butoxycarbonyl)amino)pentanoic acid 
• 254882-55-8 D-hPhe-3-aminoquinoline 
• 254882-54-7 N-tert-butoxycarbonyl-D-homophenylalanine 3-quinolylamide 
• 100564-78-1 (2R)-(tert-butoxycarbonylamino)-4-phenylbutanoic acid 
• 580-17-6 3-aminoquinoline 

Relevant articles and documents

Addressing the stability of C-capped dipeptide efflux pump inhibitors that potentiate the activity of levofloxacin in Pseudomonas aeruginosa

Synthetic optimization of a biologically labile class of dipeptides that function as efflux pump inhibitors to potentiate the antibacterial agent levofloxacin in Pseudomonas aeruginosa has led to the discovery of a related series of compounds that are completely stable in a variety of biological matrices. Other than the stability profile, the in vitro profile of the new series is essentially identical to that observed with the original one. A prototypical compound from the new series demonstrates potentiation in an in vivo model of infection.