870606-29-4 Usage
Uses
Used in Pharmaceutical Industry:
5-Chloro-3-iodo-2-methylaniline is used as a key intermediate in the synthesis of various pharmaceuticals. Its unique reactivity and properties enable the development of new drugs with improved therapeutic effects and reduced side effects.
Used in Agrochemical Industry:
In the agrochemical industry, 5-chloro-3-iodo-2-methylaniline serves as a building block for the production of agrochemicals, such as pesticides and herbicides. Its unique properties contribute to the development of more effective and environmentally friendly agrochemicals.
Used in Dye Industry:
5-Chloro-3-iodo-2-methylaniline is used as a precursor in the production of dyes. Its unique molecular structure allows for the creation of dyes with specific color properties and improved stability.
Used in Organic Compounds Synthesis:
As a versatile building block, 5-chloro-3-iodo-2-methylaniline is used in the synthesis of various organic compounds. Its unique reactivity and properties enable the development of new organic compounds with specific applications in different industries.
Safety and Environmental Considerations:
Due to its potential toxicity and environmental impact, proper handling and disposal procedures should be followed when working with 5-chloro-3-iodo-2-methylaniline. This includes the use of appropriate personal protective equipment, containment measures, and adherence to regulatory guidelines to minimize risks to human health and the environment.
Check Digit Verification of cas no
The CAS Registry Mumber 870606-29-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,7,0,6,0 and 6 respectively; the second part has 2 digits, 2 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 870606-29:
(8*8)+(7*7)+(6*0)+(5*6)+(4*0)+(3*6)+(2*2)+(1*9)=174
174 % 10 = 4
So 870606-29-4 is a valid CAS Registry Number.
870606-29-4Relevant articles and documents
Application of C-H Functionalization in the Development of a Concise and Convergent Route to the Phosphatidylinositol-3-kinase Delta Inhibitor Nemiralisib
Bream, Robert N.,Clark, Hugh,Edney, Dean,Harsanyi, Antal,Hayler, John,Ironmonger, Alan,Mc Cleary, Nadine,Phillips, Natalie,Priestley, Catherine,Roberts, Alastair,Rushworth, Philip,Szeto, Peter,Webb, Michael R.,Wheelhouse, Katherine
, p. 529 - 540 (2021/03/01)
This paper describes the development of an improved and scalable method for the manufacture of nemiralisib, a phosphatidylinositol-3-kinase delta inhibitor. Incorporation of three consecutive catalytic reactions, including a palladium-catalyzed C-H functionalization and an iridium-catalyzed borylation, significantly simplified and shortened the synthetic sequence. The revised route was successfully implemented in a pilot plant on a multikilogram scale to deliver >100 kg of product.
KINASE MODULATORS AND METHODS OF USE
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Page/Page column 113, (2010/02/15)
The present invention relates to compounds of the Formula I and II wherein R, R21, R25-R33, m, n, X21-X23, and Q1 are defined herein. The compounds modulate protein kinase enzymatic activity to modulate cellular activities such as proliferation, differentiation, programmed cell death, migration and chemoinvasion. Compounds of the invention inhibit, regulate and/or modulate kinases, particularly p70S6 and/or Akt kinases. Methods of using and preparing the compounds, and pharmaceutical compositions thereof, to treat kinase-dependent diseases and conditions are also an aspect of the invention.
