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870709-87-8

2-[(S)-1-(4-fluorophenyl)ethylamino]-5-methylthiazol-4(5H)-one is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 870709-87-8 Structure

  • Basic information

    1. Product Name: 2-[(S)-1-(4-fluorophenyl)ethylamino]-5-methylthiazol-4(5H)-one
    2. Synonyms: 2-[(S)-1-(4-fluorophenyl)ethylamino]-5-methylthiazol-4(5H)-one
    3. CAS NO:870709-87-8
    4. Molecular Formula:
    5. Molecular Weight: 252.312
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 870709-87-8.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: 2-[(S)-1-(4-fluorophenyl)ethylamino]-5-methylthiazol-4(5H)-one(CAS DataBase Reference)
    10. NIST Chemistry Reference: 2-[(S)-1-(4-fluorophenyl)ethylamino]-5-methylthiazol-4(5H)-one(870709-87-8)
    11. EPA Substance Registry System: 2-[(S)-1-(4-fluorophenyl)ethylamino]-5-methylthiazol-4(5H)-one(870709-87-8)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 870709-87-8(Hazardous Substances Data)

870709-87-8 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 870709-87-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,7,0,7,0 and 9 respectively; the second part has 2 digits, 8 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 870709-87:
(8*8)+(7*7)+(6*0)+(5*7)+(4*0)+(3*9)+(2*8)+(1*7)=198
198 % 10 = 8
So 870709-87-8 is a valid CAS Registry Number.

870709-87-8Relevant articles and documents

Further studies with the 2-amino-1,3-thiazol-4(5H)-one class of 11β-hydroxysteroid dehydrogenase type 1 inhibitors: Reducing pregnane X receptor activity and exploring activity in a monkey pharmacodynamic model

Fotsch, Christopher,Bartberger, Michael D.,Bercot, Eric A.,Chen, Michelle,Cupples, Rod,Emery, Maury,Fretland, Jenne,Guram, Anil,Hale, Clarence,Han, Nianhe,Hickman, Dean,Hungate, Randall W.,Hayashi, Michael,Komorowski, Renee,Liu, Qingyian,Matsumoto, Guy,St. Jean Jr., David J.,Ursu, Stefania,Véniant, Murielle,Xu, Guifen,Ye, Qiuping,Yuan, Chester,Zhang, Jiandong,Zhang, Xiping,Tu, Hua,Wang, Minghan

experimental part, p. 7953 - 7967 (2009/12/07)

A series of compounds containing the 2-amino-1,3-thiazol-4(5H)-one core were found to be potent inhibitors of the enzyme 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1). One of our lead compounds from this series activated the human nuclear xenobiotic

INHIBITORS OF 11-BETA-HYDROXY STEROID DEHYDROGENASE TYPE 1

-

Page/Page column 177, (2008/06/13)

The present invention relates to thiazolinones and also to pharmaceutical compositions comprising the compounds, as well as methods of use of the compounds for treatment of disorders associated with human 11-β-hydroxysteroid dehydrogenase type 1 enzyme an

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