87077-53-0

Basic information

• Product Name: 1-(4-tertiobutyl)phenyl-2-methyl-2-propanol
• CAS NO: 87077-53-0
• Molecular Weight: 206.328
• Mol File: 87077-53-0.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 1-(4-tertiobutyl)phenyl-2-methyl-2-propanol(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(4-tertiobutyl)phenyl-2-methyl-2-propanol(87077-53-0)
• EPA Substance Registry System: 1-(4-tertiobutyl)phenyl-2-methyl-2-propanol(87077-53-0)

Safety Data

• Hazardous Substances Data: 87077-53-0(Hazardous Substances Data)

Usage

Physical state

White solid

Uses

a. Fragrance ingredient
b. Solvent
c. Antifoaming agent

Derived from

Phenol and isopropyl alcohol

Chemical groups

a. tert-butyl group
b. Methyl group

Safety precautions

a. Can cause skin and eye irritation
b. Handle with care
c. Use in well-ventilated areas
d. Wear appropriate protective equipment

Upstream product

• 3549-23-3 methyl 2-(4-tert-butylphenyl)acetate 
• 75-16-1 methylmagnesium bromide 
• 123-42-2 4-Hydroxy-4-methyl-2-pentanone 
• 19692-45-6 4-tert-butylbenzyl chloride 

Relevant articles and documents

Use of 5-hydroxy-4H-benzo[1,4]oxazin-3-ones as β2-adrenoceptor agonists

Novel β2-agonists with a 5-hydroxy-4H-benzo[1,4]oxazin-3-one moiety as head group are described. Systematic chemical variations at the phenethylamine residue of these compounds lead to the discovery of compound 6m as potent, full agonist of the β2-adrenoceptor with a high β1/β2-selectivity. Molecular modeling revealed an interaction between the carboxylic acid group of 6m and a lysine residue (K305) of the β2-receptor as putative explanation for the high observed selectivity. Further, compound 6m displayed in a guinea pig in vivo model a complete reversal of acetylcholine induced bronchoconstriction which lasted over the complete study time of 5 h.