870812-92-3

Usage

Uses

Intermediate in the production of cell death regulators and apoptosis promoters.

Upstream product

• 78663-07-7 N-(benzyloxycarbonyl)-D-aspartic acid 
• 123673-31-4 (R)-3-(benzyloxycarbonylamino)-4-hydroxybutanoic acid 
• 75443-62-8 benzyl N-[(3R)-2,5-dioxotetrahydrofuran-3-yl]carbamate 
• 110-91-8 morpholine 
• 118399-28-3 (R)-4-benzyloxycarbonylamino-4,5-dihydro-2(3H)-furanone 

Downstream Products

• 870812-94-5 (1R)-3-(4-morpholinyl)-3-oxo-1-((phenylsulfanyl)methyl)propylamine 
• 872866-27-8 4-((R)-3-(morpholin-4-yl)-3-oxo-1-phenylsulfanylmethylpropylamino)-3-nitrobenzenesulfonamide 
• 872866-28-9 4-((R)-3-(morpholin-4-yl)-1-phenylsulfanylmethylpropylamino)-3-nitrobenzenesulfonamide 
• 1027345-09-0 C₁₇H₂₄N₂O₇S 
• 870812-93-4 benzyl (1R)-3-(4-morpholinyl)-3-oxo-1-((phenylsulfanyl)methyl)propylcarbamate 

Relevant academic research and scientific papers

CHEMICAL COMPOUNDS

The present invention relates to compounds of Formula (I): and to their salts, pharmaceutical compositions, methods of use, and methods for their preparation. These compounds inhibit Bcl-2 and/or Bcl-XL activities and may be used for the treatment of cancer.

ARYLSULFONAMIDE COMPOUNDS

The invention relates generally to small molecules that mimic the biological activity of certain peptides and proteins, to compositions containing them and to their use. In particular, the invention relates to compounds of the general formula (I) that mim

N-sulfonylcarboximidamide apoptosis promoters

Compounds having the formula are apoptosis promoters. Also disclosed are methods of making the compounds, compositions containing the compounds, and methods of treatment using the compounds.