870838-56-5

Basic information

• Product Name: 1-(4-BROMO-2-METHOXYPHENYL)-4-METHYL-1H-IMIDAZOLE
• Synonyms: 1-(4-BROMO-2-METHOXYPHENYL)-4-METHYL-1H-IMIDAZOLE;1-(4-broMo-2-Methoxyphenyl)-4-Methyl-1H-iMidazole hydrochloride
• CAS NO: 870838-56-5
• Molecular Formula: C₁₁H₁₁BrN₂O
• Molecular Weight: 267.13
• Mol File: 870838-56-5.mol
• Article Data: 11

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 1-(4-BROMO-2-METHOXYPHENYL)-4-METHYL-1H-IMIDAZOLE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(4-BROMO-2-METHOXYPHENYL)-4-METHYL-1H-IMIDAZOLE(870838-56-5)
• EPA Substance Registry System: 1-(4-BROMO-2-METHOXYPHENYL)-4-METHYL-1H-IMIDAZOLE(870838-56-5)

Safety Data

• Hazardous Substances Data: 870838-56-5(Hazardous Substances Data)

Usage

General Description

1-(4-Bromo-2-methoxyphenyl)-4-methyl-1H-imidazole is a chemical compound with the molecular formula C11H10BrN2O and a systematic name of 1-(4-bromo-2-methoxyphenyl)-4-methyl-1H-imidazole. It is an imidazole derivative with a bromo-methoxyphenyl group and a methyl group attached to the imidazole ring. 1-(4-Bromo-2-methoxyphenyl)-4-methyl-1H-imidazole is commonly used in pharmaceutical research and drug development due to its potential biological activities such as anti-inflammatory, antimicrobial, and anti-cancer properties. It is often employed as a building block in the synthesis of various pharmaceutical compounds and can also be used as a ligand in coordination chemistry for the preparation of metal complexes. Additionally, it has also been studied for its potential applications in materials science and organic electronic devices.

InChI:InChI=1S/C11H11BrN2O/c1-8-6-14(7-13-8)10-4-3-9(12)5-11(10)15-2/h3-7H,1-2H3

Upstream product

• 870838-53-2 1-{[4-bromo-2-(methyloxy)phenyl]amino}-2-propanone 
• 870838-52-1 o-bromotrifluoroacetanilide 
• 59557-91-4 4-bromo-2-methoxyaniline 
• 1009-36-5 2-chloro-5-nitroanisole 
• 90-04-0 2-methoxy-phenylamine 
• 77337-82-7 1-bromo-2-methoxy-4-nitrobenzene 
• 958245-18-6 3-methoxy-4-(4-methyl-1H-imidazol-1-yl)aniline 
• 958245-17-5 1-(2-methoxy-4-nitrophenyl)-4-methyl-1H-imidazole 
• 454-16-0 1-fluoro-2-methoxy-4-nitrobenzene 
• 1145786-43-1 [4-bromo-2-(methyloxy)phenyl](2-oxopropyl)formamide 
• 822-36-6 4-methyl-1H-imidazole 
• 791642-68-7 4-bromo-1-iodo-2-methoxybenzene 
• 870838-55-4 N-(4-bromo-2-methoxyphenyl)-N-(2-oxopropyl)acetamide 

Downstream Products

• 870838-57-6 1-(4-iodine-2-methoxyphenyl)-4-methyl-1H-imidazole 
• 1145786-45-3 [4-(4-methyl-1H-imidazol-1-yl)-3-(methyloxy)phenyl]boronic acid 
• 1145786-44-2 4-methyl-1-[2-(methyloxy)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]-1H-imidazole 
• 1145785-08-5 N-(3-biphenylylmethyl)-6-[4-(4-methyl-1H-imidazol-1-yl)-3-(methyloxy)phenyl]-3-pyridazinamine 
• 1262193-88-3 1-[3-[3-methoxy-4-(4-methyl-1H-imidazol-1-yl)phenyl]-1-(1-methylethyl)-1H-1,2,4-triazol-5-yl]-3-phenyl-piperidine hydrochloride 
• 1315141-35-5 C₂₀H₁₈N₄O₂ 
• 1315141-32-2 C₂₁H₂₀N₄O 
• 1240608-19-8 [2-(4-fluorophenyl)-1H-benzoimidazol-4-yl]-[3-methoxy-4-(4-methylimidazol-1-yl)phenyl]amine 
• 1240608-49-4 [1-benzyl-2-(4-fluorophenyl)-1H-benzoimidazol-4-yl]-[3-methoxy-4-(4-methylimidazol-1-yl)phenyl]amine 
• 1240607-49-1 (1,2-dimethyl-1H-benzoimidazol-4-yl)-[3-methoxy-4-(4-methylimidazol-1-yl)phenyl]amine 
• 870838-58-7 tert-butyl [3-methoxy-4-(4-methyl-1H-imidazol-1-yl)phenyl]propiolic acid ester 
• 1262193-86-1 5,6-dihydro-2-[3-methoxy-4-(4-methyl-1H-imidazol-1-yl)phenyl]-8-[2-(trifluoromethyl)phenyl]-8H-[1,2,4]triazolo[5,1-c][1,4]oxazine 
• 1242315-05-4 5,6,7,8-tetrahydro-2-[3-methoxy-4-(4-methyl-1H-imidazol-1-yl)phenyl]-8-[2-(trifluoromethyl)phenyl]-[1,2,4]triazolo[1,5-a]pyridine 
• 1262193-74-7 8-(4-fluoro-2-methylphenyl)-5,6,7,8-tetrahydro-2-[3-methoxy-4-(4-methyl-1H-imidazol-1-yl)phenyl]-[1,2,4]triazolo[1,5-a]pyridine 

Relevant articles and documents

Design and Synthesis of a Novel Series of Bicyclic Heterocycles As Potent γ-Secretase Modulators

The design and the synthesis of several chemical subclasses of imidazole containing γ-secretase modulators (GSMs) is described. Conformational restriction of pyridone 4 into bicyclic pyridone isosteres has led to compounds with high in vitro and in vivo p

Pyridazine-derived γ-secretase modulators

SAR of a novel series of pyridazine-derived γ-secretase modulators is described. Compound 25 was found to be a potent modulator in vitro, which on further profiling, was found to decrease Aβ42 and Aβ40, and maintain the levels of total Aβ. Furthermore, 25

SUBSTITUTED TRIAZOLE AND IMIDAZOLE DERIVATIVES AS GAMMA SECRETASE MODULATORS

The present invention is concerned with novel substituted triazole and imidazole derivatives of Formula (I) wherein R1, R2, A1, A2, A3, A4, X, and Het1 have the meaning defined in the claims. The compounds according to the present invention are useful as gamma secretase modulators. The invention further relates to processes for preparing such novel compounds, pharmaceutical compositions comprising said compounds as an active ingredient as well as the use of said compounds as a medicament.