870849-11-9

Usage

Uses

Used in Organic Synthesis:
(Tetrahydrofuran-2-yl)(phenyl)methanamine serves as a key intermediate in the synthesis of various organic compounds due to its unique structural features. Its reactivity and stability make it a valuable building block for creating complex molecules with specific properties.
Used in Pharmaceutical Industry:
In the pharmaceutical sector, (tetrahydrofuran-2-yl)(phenyl)methanamine may be utilized as a precursor for the development of new drugs. Its structural components can be manipulated to target specific biological pathways or receptors, potentially leading to the creation of novel therapeutic agents.
Used in Chemical Research:
(Tetrahydrofuran-2-yl)(phenyl)methanamine can also be employed in chemical research to study the properties and reactions of amine compounds. Understanding its behavior in different conditions can contribute to the advancement of chemical knowledge and the development of new synthetic methods or applications.
Used in Material Science:
(tetrahydrofuran-2-yl)(phenyl)methanamine may find applications in material science, where its unique structure could be leveraged to create new materials with specific properties, such as improved conductivity, strength, or chemical resistance.
Used in Industrial Processes:
(Tetrahydrofuran-2-yl)(phenyl)methanamine could be integrated into various industrial processes, potentially enhancing the efficiency or effectiveness of certain chemical reactions or production methods. Its versatility and reactivity make it a candidate for optimization and innovation in industrial applications.

Upstream product

• 7699-79-8 benzhydrylidene-benzyl-amine 
• 100-46-9 benzylamine 
• 13544-26-8 6-phenyl-3,4-dihydro-2H-pyran 
• 4203-44-5 2-phenyltetrahydropyran 
• 141957-79-1 phenyl(tetrahydrofuran-2-yl)methanone 
• 1197006-09-9 C₁₇H₁₉NO₃S 

Downstream Products

• 1197006-10-2 C₁₈H₁₉BrN₂O₂ 

Relevant academic research and scientific papers

Transition-metal-free C(sp3)-H/C(sp3)-H dehydrogenative coupling of saturated heterocycles with: N-benzyl imines

A unique C(sp3)-H/C(sp3)-H dehydrocoupling of N-benzylimines with saturated heterocycles is described. Using super electron donor (SED) 2-azaallyl anions and aryl iodides as electron acceptors, single-electron-transfer (SET) generates an aryl radical. Hydrogen atom transfer (HAT) from saturated heterocycles or toluenes to the aryl radical generates alkyl radicals or benzylic radicals, respectively. The newly formed alkyl radicals and benzylic radicals couple with the 2-azaallyl radicals with formation of new C-C bonds. Experimental evidence supports the key hydrogen-abstraction by the aryl radical, which determines the chemoselectivity of the radical-radical coupling reaction. It is noteworthy that this procedure avoids the use of traditional strong oxidants and transition metals. This journal is

Ring-Contraction Reaction of Substituted Tetrahydropyrans via Dehydrogenative Dual Functionalization by Nitrite-Catalyzed Double Activation of Bromine

A nitrite-catalyzed ring contraction reaction of substituted tetrahydrofurans by oxidation of bromide under aerobic conditions as a dehydrogenative dual functionalization was developed to provide 2-acyltetrahydrofurans in good yields. On the other hand, the oxidation reaction of 1-substituted isochromans occurred via the bromohydroxylation to give 1-(dibromoalkyl)-1-hydroxyisochromans in high yields.

BICYCLIC HETEROCYCLE DERIVATIVES AND USE THEREOF AS GPR119 MODULATORS

The present invention relates to Bicyclic Heterocycle Derivatives of formula (I), compositions comprising a Bicyclic Heterocycle Derivative, and methods of using the Bicyclic Heterocycle Derivatives for treating or preventing obesity, diabetes, a metabolic disorder, a cardiovascular disease or a disorder related to the activity of GPR1 19 in a patient.