141957-79-1Relevant articles and documents
Ring-Contraction Reaction of Substituted Tetrahydropyrans via Dehydrogenative Dual Functionalization by Nitrite-Catalyzed Double Activation of Bromine
Watanabe, Kazuhiro,Hamada, Tsukasa,Moriyama, Katsuhiko
, p. 5803 - 5807 (2018)
A nitrite-catalyzed ring contraction reaction of substituted tetrahydrofurans by oxidation of bromide under aerobic conditions as a dehydrogenative dual functionalization was developed to provide 2-acyltetrahydrofurans in good yields. On the other hand, the oxidation reaction of 1-substituted isochromans occurred via the bromohydroxylation to give 1-(dibromoalkyl)-1-hydroxyisochromans in high yields.
C(sp3)-H Bond Acylation with N -Acyl Imides under Photoredox/ Nickel Dual Catalysis
Kerackian, Taline,Reina, Antonio,Krachko, Tetiana,Boddaert, Hugo,Bouyssi, Didier,Monteiro, Nuno,Amgoune, Abderrahmane
supporting information, p. 1531 - 1536 (2020/10/21)
A novel Ni/photoredox-catalyzed acylation of aliphatic substrates, including simple alkanes and dialkyl ethers, has been developed. The method combines C-N bond activation of amides with a radical relay mechanism involving hydrogen-atom transfer. The protocol is operationally simple, employs bench-stable N -acyl imides as acyl-transfer reagents, and permits facile access to alkyl ketones under very mild conditions.
Photocatalytic α-Acylation of Ethers
Sun, Zhongdong,Kumagai, Naoya,Shibasaki, Masakatsu
supporting information, p. 3727 - 3730 (2017/07/26)
Direct coupling of ethers and acyl halides was promoted by a binary catalytic system comprising an Ir-based photocatalyst and a Ni complex under blue-light irradiation. Photocatalysts with high triplet energy directed the catalysis, and the reaction likely proceeded by triplet-triplet energy transfer from the excited photocatalysts. Chlorine radicals generated from an excited Ni complex bearing a Ni-Cl bond would be responsible for generating α-oxy radicals leading to the α-acylated ethers.
