870849-56-2 Usage
Uses
Used in Pharmaceutical Industry:
1-(4-Fluoro-3-methoxyphenyl)ethan-1-ol is used as a building block for the synthesis of pharmaceuticals due to its unique chemical properties and structural features. It can be incorporated into the development of new drugs, potentially enhancing their efficacy and selectivity.
Used in Agrochemical Industry:
In the agrochemical industry, 1-(4-Fluoro-3-methoxyphenyl)ethan-1-ol is used as a precursor for the synthesis of various agrochemicals. Its unique structure can contribute to the development of more effective and targeted pesticides or other agricultural chemicals.
Used in Fragrance Industry:
1-(4-Fluoro-3-methoxyphenyl)ethan-1-ol is used as a building block in the fragrance industry for the creation of unique and complex scents. Its distinct chemical structure allows for the development of novel fragrance compounds that can be used in various consumer products.
Overall, the diverse applications of 1-(4-Fluoro-3-methoxyphenyl)ethan-1-ol across different industries highlight its potential as a valuable chemical intermediate for the synthesis of a wide range of products.
Check Digit Verification of cas no
The CAS Registry Mumber 870849-56-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,7,0,8,4 and 9 respectively; the second part has 2 digits, 5 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 870849-56:
(8*8)+(7*7)+(6*0)+(5*8)+(4*4)+(3*9)+(2*5)+(1*6)=212
212 % 10 = 2
So 870849-56-2 is a valid CAS Registry Number.
InChI:InChI=1/C9H11FO2/c1-6(11)7-3-4-8(10)9(5-7)12-2/h3-6,11H,1-2H3
870849-56-2Relevant academic research and scientific papers
Nicewicz, David A.,Pistritto, Vincent A.,Schutzbach-Horton, Megan E.
, p. 17187 - 17194 (2020)
Nucleophilic aromatic substitution (SNAr) is a classical reaction with well-known reactivity toward electron-poor fluoroarenes. However, electron-neutral and electron-rich fluoro(hetero)arenes are considerably underrepresented. Herein, we present a method for the nucleophilic defluorination of unactivated fluoroarenes enabled by cation radical-accelerated nucleophilic aromatic substitution. The use of organic photoredox catalysis renders this method operationally simple under mild conditions and is amenable to various nucleophile classes, including azoles, amines, and carboxylic acids. Select fluorinated heterocycles can be functionalized using this method. In addition, the late-stage functionalization of pharmaceuticals is also presented. Computational studies demonstrate that the site selectivity of the reaction is dictated by arene electronics.
