87088-48-0

Basic information

• Product Name: 2-(Dimethoxy-phosphoryl)-3-(4-hydroxy-4-methyl-2-methylene-cyclohexyl)-propionic acid methyl ester
• Synonyms: 2-(Dimethoxy-phosphoryl)-3-(4-hydroxy-4-methyl-2-methylene-cyclohexyl)-propionic acid methyl ester
• CAS NO: 87088-48-0
• Molecular Weight: 320.323
• Mol File: 87088-48-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-(Dimethoxy-phosphoryl)-3-(4-hydroxy-4-methyl-2-methylene-cyclohexyl)-propionic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(Dimethoxy-phosphoryl)-3-(4-hydroxy-4-methyl-2-methylene-cyclohexyl)-propionic acid methyl ester(87088-48-0)
• EPA Substance Registry System: 2-(Dimethoxy-phosphoryl)-3-(4-hydroxy-4-methyl-2-methylene-cyclohexyl)-propionic acid methyl ester(87088-48-0)

Safety Data

• Hazardous Substances Data: 87088-48-0(Hazardous Substances Data)

Upstream product

• 55168-74-6 trimethyl 2-phosphonoacrylate 
• 110-93-0 6-Methyl-hept-5-en-2-on 
• 87088-47-9 2-(Dimethoxy-phosphoryl)-4-isopropenyl-7-oxo-octanoic acid methyl ester 

Relevant articles and documents

Ene Reactions of 2-Phosphonoacrylates

Trimethyl 2-phosphonoacrylate (1a) undergoes EtAlCl2-catalyzed ene reactions in high yield at 0 deg C with most classes of alkenes.The products are useful reagents for the phosphonate modification of the Wittig reaction.EtAlCl2-catalyzed ene reaction of 1a with 6-methyl-5-hepten-2-one (18) at -78 deg C gives 19, which undergoes an intramolecular Wittig reaction to give 21.Ethyl α-methylene-1-cyclohexenebutanoate (16) undergoes a Lewis acid initiated cyclization to give the cyclopropane 30 and octalins 31 and 32.