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AC-262536 is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 4-[(3-endo)-3-Hydroxy-8-azabicyclo[3.2.1]oct-8-yl]naphthalene-1-carbonitrile;AC-262536;AC-262,356;4-(3-endo-Hydroxy-8-azabicyclo[3.2.1]oct-8-yl)naphthalene-1-carbonitrile

    Cas No: 870888-46-3

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  • 870888-46-3 Structure
  • Basic information

    1. Product Name: AC-262536
    2. Synonyms: 4-[(3-endo)-3-Hydroxy-8-azabicyclo[3.2.1]oct-8-yl]naphthalene-1-carbonitrile;AC-262536;AC-262,356;4-(3-endo-Hydroxy-8-azabicyclo[3.2.1]oct-8-yl)naphthalene-1-carbonitrile
    3. CAS NO:870888-46-3
    4. Molecular Formula: C18H18N2O
    5. Molecular Weight: 278.35
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 870888-46-3.mol
  • Chemical Properties

    1. Melting Point: 158-162°C
    2. Boiling Point: 526.0±45.0 °C(Predicted)
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: 1.28±0.1 g/cm3(Predicted)
    6. Refractive Index: N/A
    7. Storage Temp.: 2-8°C
    8. Solubility: N/A
    9. PKA: 14.73±0.20(Predicted)
    10. CAS DataBase Reference: AC-262536(CAS DataBase Reference)
    11. NIST Chemistry Reference: AC-262536(870888-46-3)
    12. EPA Substance Registry System: AC-262536(870888-46-3)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany: 3
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 870888-46-3(Hazardous Substances Data)

870888-46-3 Usage

Uses

AC-262536 is a hydrocarbon organic matter and can be used as pharmaceutical intermediates.

Check Digit Verification of cas no

The CAS Registry Mumber 870888-46-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,7,0,8,8 and 8 respectively; the second part has 2 digits, 4 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 870888-46:
(8*8)+(7*7)+(6*0)+(5*8)+(4*8)+(3*8)+(2*4)+(1*6)=223
223 % 10 = 3
So 870888-46-3 is a valid CAS Registry Number.

870888-46-3 Well-known Company Product Price

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  • Sigma-Aldrich

  • (96443)  4-[(3-endo)-3-Hydroxy-8-azabicyclo[3.2.1]oct-8-yl]naphthalene-1-carbonitrile  analytical standard

  • 870888-46-3

  • 96443-25MG

  • 1,914.12CNY

  • Detail

870888-46-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 16, 2017

Revision Date: Aug 16, 2017

1.Identification

1.1 GHS Product identifier

Product name 4-(3-hydroxy-8-azabicyclo[3.2.1]oct-8-yl)naphthalene-1-carbonitrile

1.2 Other means of identification

Product number -
Other names AC-262536

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:870888-46-3 SDS

870888-46-3Relevant articles and documents

Practical and regioselective amination of arenes using alkyl amines

Ruffoni, Alessandro,Juliá, Fabio,Svejstrup, Thomas D.,McMillan, Alastair J.,Douglas, James J.,Leonori, Daniele

, p. 426 - 433 (2019/05/01)

The formation of carbon–nitrogen bonds for the preparation of aromatic amines is among the top five reactions carried out globally for the production of high-value materials, ranging from from bulk chemicals to pharmaceuticals and polymers. As a result of this ubiquity and diversity, methods for their preparation impact the full spectrum of chemical syntheses in academia and industry. In general, these molecules are assembled through the stepwise introduction of a reactivity handle in place of an aromatic C–H bond (that is, a nitro group, halogen or boronic acid) and a subsequent functionalization or cross-coupling. Here we show that aromatic amines can be constructed by direct reaction of arenes and alkyl amines using photocatalysis, without the need for pre-functionalization. The process enables the easy preparation of advanced building blocks, tolerates a broad range of functionalities, and multigram scale can be achieved via a batch-to-flow protocol. The merit of this strategy as a late-stage functionalization platform has been demonstrated by the modification of several drugs, agrochemicals, peptides, chiral catalysts, polymers and organometallic complexes.

Synthesis, structure-activity relationships, and characterization of novel nonsteroidal and selective androgen receptor modulators

Schlienger, Nathalie,Lund, Birgitte W.,Pawlas, Jan,Badalassi, Fabrizio,Bertozzi, Fabio,Lewinsky, Rasmus,Fejzic, Alma,Thygesen, Mikkel B.,Tabatabaei, Ali,Bradley, Stefania Risso,Gardell, Luis R.,Piu, Fabrice,Olsson, Roger

supporting information; experimental part, p. 7186 - 7191 (2010/07/04)

Herein we describe the discovery of ACP-105 (1), a novel and potent nonsteroidal selective androgen receptor modulator (SARM) with partial agonist activity relative to the natural androgen testosterone. Compound 1 was developed from a series of compounds found in a HTS screen using the receptor selection and amplification technology (R-SAT). In vivo, 1 improved anabolic parameters in a 2-week chronic study in castrated male rats. In addition to compound 1, a number of potent antiandrogens were discovered from the same series of compounds whereof one compound, 13, had antagonist activity at the AR T877A mutant involved in prostate cancer.

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