870997-87-8

Basic information

• Product Name: N-Methyl-2-aminopyridine-3-carboxamide
• Synonyms: N-Methyl-2-aminonicotinamide;N-Methyl-2-aminopyridine-3-carboxamide;N-methyl-2-amino-3-nicotinamide;3-Pyridinecarboxamide,2-amino-N-methyl-;2-Amino-N-methylnicotinamide;2-amino-N-methylpyridine-3-carboxamide
• CAS NO: 870997-87-8
• Molecular Formula: C₇H₉N₃O
• Molecular Weight: 151.17
• Mol File: 870997-87-8.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 373.1 °C at 760 mmHg
• Flash Point: 179.4 °C
• Appearance: /
• Density: 1.206
• Vapor Pressure: 9.19E-06mmHg at 25°C
• Refractive Index: 1.588
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• Solubility: DMSO (Slightly), Methanol (Slightly, Sonicated)
• CAS DataBase Reference: N-Methyl-2-aminopyridine-3-carboxamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-Methyl-2-aminopyridine-3-carboxamide(870997-87-8)
• EPA Substance Registry System: N-Methyl-2-aminopyridine-3-carboxamide(870997-87-8)

Safety Data

• Hazardous Substances Data: 870997-87-8(Hazardous Substances Data)

Usage

Uses

2-Amino-N-methylpyridine-3-carboxamide is used in preparation of triazolopyrazine derivatives and analogs for use as c-MET kinase activity inhibitors.

InChI:InChI=1/C7H9N3O/c1-9-7(11)5-3-2-4-10-6(5)8/h2-4H,1H3,(H2,8,10)(H,9,11)

Upstream product

• 5345-47-1 2-aminopyridin-3-carboxylic acid 
• 74-89-5 methylamine 
• 593-51-1 methylamine hydrochloride 
• 13362-26-0 2-aminopyridine-3-carboxylic acid ethyl ester 

Downstream Products

• 41803-82-1 3-Methyl-2-phenylpyrido<2,3-d>pyrimidin-4(3H)-on 

Relevant articles and documents

BENZOXAZINONE DERIVATIVES FOR THE TREATMENT OF GLYTL MEDIATED DISORDERS

The present invention relates to benzoxazinone derivatives, processes for their preparation, pharmaceutical compositions and medicaments containing them and to their use in treating disorders mediated by GlyT1, including neurological and neuropsychiatric disorders, in particular psychoses, dementia or attention deficit disorder.

QUINAZOLINE DERIVATIVE

This invention provides a compound or its pharmaceutically-acceptable salt of formula (I) wherein R 1 represents a lower alkyl group et al; R 2 and R 3 are same and different and represents hydrogen atm et al; R 4 represents the substituent of the formula (II) et al; X 1 represents NH, O or S; Y represents N or C; Ar is a divalent substituent derived from aryl et al, by removing two hydrogen atoms therefrom; the ring A represents a 5- or 6-membered heteroaryl group; this compounds has a histamine-H3 receptor antagonistic effect or a histamine-H3 receptor inverse-agonistic effect and is useful for preventive or remedy of metabolic system diseases, circulatory system diseases or nervous system diseases.

Syntheses and diuretic activity of 1,2-dihydro-2-(3-pyridyl)-3H-pyrido[2,3-d]pyrimidin-4-one and related compounds

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