87118-53-4

Basic information

• Product Name: Pentanedioic acid, 3-hydroxy-, monomethyl ester, (R)-
• CAS NO: 87118-53-4
• Molecular Formula: C6H10O5
• Molecular Weight: 162.142
• Mol File: 87118-53-4.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: Pentanedioic acid, 3-hydroxy-, monomethyl ester, (R)-(CAS DataBase Reference)
• NIST Chemistry Reference: Pentanedioic acid, 3-hydroxy-, monomethyl ester, (R)-(87118-53-4)
• EPA Substance Registry System: Pentanedioic acid, 3-hydroxy-, monomethyl ester, (R)-(87118-53-4)

Safety Data

• Hazardous Substances Data: 87118-53-4(Hazardous Substances Data)

Upstream product

• 90613-44-8 methyl 3-acetoxypentanedioate 
• 7250-55-7 dimethyl 3-hydroxypentanedioate 

Downstream Products

• 87118-55-6 (R)-((3-tert-butyldiphenylsillyl)oxy)pentanedioic acid monomethyl ester 
• 106064-61-3 (R)-3-[(tert-butyldiphenylsilyl)oxy]pentanoic acid lactone 
• 106064-60-2 (R)-3-[(tert-butyldiphenylsilyl)oxy]pentanoic acid methyl ester 
• 91424-38-3 (3S,1'R)-N-(1'-phenylethyl)-3-<(tert-butyldimethylsilyl)oxy>-4-carbomethoxybutanamide 
• 91424-37-2 (3R,1'R)-N-(1'-phenylethyl)-3-<(tert-butyldimethylsilyl)oxy>-4-carbomethoxybutanamide 
• 18990-98-2 (R)-Hexane-1,3,6-triol 
• 87118-61-4 (R)-4-{2-[2-(tert-Butyl-dimethyl-silanyloxy)-ethyl]-[1,3]dioxolan-2-yl}-3-(tert-butyl-diphenyl-silanyloxy)-butyraldehyde 
• 87118-60-3 (R)-4-{2-[2-(tert-Butyl-dimethyl-silanyloxy)-ethyl]-[1,3]dioxolan-2-yl}-3-(tert-butyl-diphenyl-silanyloxy)-butyric acid methyl ester 
• 87118-62-5 (2E,4E)-(R)-8-{2-[2-(tert-Butyl-dimethyl-silanyloxy)-ethyl]-[1,3]dioxolan-2-yl}-7-(tert-butyl-diphenyl-silanyloxy)-octa-2,4-dienoic acid methyl ester 
• 87118-63-6 (E)-3-{3-[(R)-3-{2-[2-(tert-Butyl-dimethyl-silanyloxy)-ethyl]-[1,3]dioxolan-2-yl}-2-(tert-butyl-diphenyl-silanyloxy)-propyl]-oxiranyl}-acrylic acid methyl ester 
• 87118-59-0 (R)-3-(tert-Butyl-diphenyl-silanyloxy)-4-[2-(2-hydroxy-ethyl)-[1,3]dioxolan-2-yl]-butyric acid methyl ester 
• 87118-56-7 (R)-3-(tert-Butyl-diphenyl-silanyloxy)-6-tert-butylsulfanylcarbonyl-5-oxo-hexanoic acid methyl ester 
• 87118-58-9 (R)-3-(tert-Butyl-diphenyl-silanyloxy)-4-(2-carboxymethyl-[1,3]dioxolan-2-yl)-butyric acid methyl ester 
• 87118-57-8 (R)-3-(tert-Butyl-diphenyl-silanyloxy)-4-(2-tert-butylsulfanylcarbonylmethyl-[1,3]dioxolan-2-yl)-butyric acid methyl ester 

Relevant articles and documents

3-Hydroxyglutarate and β,γ-Epoxy Esters as Substrates for Pig Liver Esterase (PLE) and α-Chymotrypsin

The pH dependence of the α-chymotrypsin-catalyzed hydrolysis of dimethyl 3-hydroxyglutarate (3) has been studied.The e.e. was determined by HPLC analysis of diastereoisomeric camphanoic-acid derivatives.Kinetic resolution of the β,γ-epoxy esters 10 and 24 by pig liver esterase has been shown to provide an alternative access to chiral β-hydroxy esters and acids of high optical purity.By this latter method, the unnatural enantiomer of γ-amino-β-hydroxybutyric acid (GABOB) has been sinthesized.Finally, dimethyl meso-3,4-epoxyadipate (19) was hydrolyzed by pig liver esterase with almost 100 percent selectivity.

Enzymes in organic synthesis. 44. Stereoselective pig liver esterase-catalyzed hydrolyses of 3-substituted glutarate diesters of compactin-synthon interest

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