87128-98-1Relevant academic research and scientific papers
Synthesis of paclitaxel. 1. synthesis of the abc ring of paclitaxel by SmI2-mediated cyclization
Fukaya, Keisuke,Tanaka, Yuta,Sato, Ayako C.,Kodama, Keisuke,Yamazaki, Hirohisa,Ishimoto, Takeru,Nozaki, Yasuyoshi,Iwaki, Yuki M.,Yuki, Yohei,Umei, Kentaro,Sugai, Tomoya,Yamaguchi, Yu,Watanabe, Ami,Oishi, Takeshi,Sato, Takaaki,Chida, Noritaka
, p. 2570 - 2573 (2015/06/16)
A convergent synthesis of the ABC ring of antitumor natural product paclitaxel (Taxol) is described. SmI2-mediated reductive cyclization of an allylic benzoate possessing an aldehyde function, synthesized from tri-O-acetyl-d-glucal and 1,3-cyclohexanedione, smoothly afforded the highly strained 6-8-6 tricarbocyclic structure in 66% yield.
Glycinoeclepins, Natural Hatching Stimuli for the Soybean Cyst Nematode, Heterodera Glycines. II. Structural Elucidation
Masamune, Tadashi,Fukuzawa, Akio,Furusaki, Akio,Ikura, Mitsuhiko,Matsue, Hideki,et al.
, p. 1001 - 1014 (2007/10/02)
The structures of three new compounds, glycinoeclepsins A, B, and C, isolated from the hatch-stimulating extracts of kidney beans for the soybean cyst nematode, have been determined.The structures were resolved by using spectroscopic methods, especially b
Preparation of 2-exo-Hydroxy-7-oxabicyclo[2.2.1]heptanes
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, (2008/06/13)
2-exo-Hydroxy-7-oxabicyclo[2.2.1]heptanes are prepared by treating the corresponding cis-epoxycyclohexanol with acid in an inert solvent or by treating a 3-cyclohexen-1-ol which will produce the corresponding cis-epoxy alcohol successively or concurrently with an oxidizing agent and an acid in an inert solvent.
