871327-76-3

Upstream product

• 854018-88-5 4-chloro-3-(4-chloro-phenylsulfanyl)-2-methyl-1H-pyrrolo[3,2-c]pyridine 
• 105-36-2 ethyl bromoacetate 
• 234108-73-7 (2-chloro-pyridin-4-yl)-carbamic acid tert-butyl ester 
• 234108-74-8 (2-chloro-3-iodo-pyridin-4-yl)-carbamic acid tert-butyl ester 
• 854018-87-4 4-chloro-2-methyl-1H-pyrrolo[3,2-c]pyridine 
• 854018-86-3 tert-butyl (2-chloro-3-prop-1-yn-1-ylpyridin-4-yl)carbamate 
• 106-54-7 p-Chlorothiophenol 
• 933-01-7 4-chloro-benzenesulfenyl chloride 

Downstream Products

• 871327-78-5 [4-chloro-3-(4-chloro-phenylsulfonyl)-2-methyl-pyrrolo[3,2-c]pyridin-1-yl]-acetic acid ethyl ester 

Relevant academic research and scientific papers

Substituted indole-1-acetic acids as potent and selective CRTh2 antagonists-discovery of AZD1981

Novel indole-3-thio-, 3-sulfonyl- and 3-oxy-aryl-1-acetic acids are reported which are potent, selective antagonists of the chemoattractant receptor-homologous expressed on Th2 lymphocytes receptor (CRTh2 or DP2). Optimization required maintenance of high

PYRROLOPYRIDINE DERIVATIVES AND USE THEREOF FOR TREATING DISEASES MEDIATED BY PROSTAGLANDIN D2 (PGD2)

Compounds of formula (Ia) or (Ib): or pharmaceutically acceptable salts, hydrates, solvates, complexes or prodrugs thereof are useful in the treatment of allergic diseases such as asthma, allergic rhinitis and atopic dermatitis.

1-ACETIC ACID-INDOLE, -INDAZOLE AND-BENZIMIDAZOLE DERIVATIVES USFUL FOR THE TREATMENT OF RESPIRATORY DISORDERS

The present invention relates to substituted indoles of formula (I) useful as pharmaceutical compounds for treating respiratory disorders.