871355-29-2

Usage

Uses

Used in Organic Synthesis:
(S)-2-bromo-7-(tert-butyldiphenylsilanyloxy)-hept-1-en-4-ol is utilized as a valuable intermediate in organic synthesis for the preparation of a wide range of functionalized compounds. Its unique structure allows for numerous synthetic transformations, contributing to the development of novel chemical entities.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, (S)-2-bromo-7-(tert-butyldiphenylsilanyloxy)-hept-1-en-4-ol is used as a key intermediate for the development of new drugs. Its structural diversity and synthetic potential make it a promising candidate for the creation of innovative therapeutic agents.
Used in Agrochemical Industry:
(S)-2-bromo-7-(tert-butyldiphenylsilanyloxy)-hept-1-en-4-ol also finds application in the agrochemical industry, where it serves as an intermediate for the development of new crop protection products. Its versatility in synthesis enables the creation of compounds with potential pesticidal, herbicidal, or fungicidal properties.
Overall, (S)-2-bromo-7-(tert-butyldiphenylsilanyloxy)-hept-1-en-4-ol is a significant compound in the fields of organic synthesis, pharmaceuticals, and agrochemicals, owing to its structural complexity and synthetic utility.

Upstream product

• 127793-62-8 4-((tert-butyldiphenylsilyl)oxy)butanal 
• 513-31-5 2-bromoallyl bromide 
• 871355-14-5 C₂₃H₃₁BrO₂Si 
• 871348-26-4 C₇H₁₃BrO₂ 

Downstream Products

• 253128-10-8 3-((2S,5S)-5-(2-((2S,4R,6R)-6-(((2S,3S,4R,5R)-5-((S)-2,3-bis((tert-butyldimethylsilyl)oxy)propyl)-4-methoxy-3-((phenylsulfonyl)methyl)tetrahydrofuran-2-yl)methyl)-4-methyl-5-methylenetetrahydro-2H-pyran-2-yl)ethyl)-4-methylenetetrahydrofuran-2-yl)propan-1-ol 
• 1424343-98-5 C₄₆H₇₁NO₈SSi₂ 
• 871357-02-7 C₃₉H₆₃NO₅Si₂ 
• 1139773-92-4 C₃₉H₆₃NO₅Si₂ 
• 871357-66-3 C₂₃H₃₇F₃O₉S₂ 
• 1424343-99-6 C₅₁H₉₀O₁₃S₂Si₂ 
• 253128-09-5 3-((2S,5S)-5-(2-((2S,4R,6R)-6-(((2S,3S,4R,5R)-5-((S)-2,3-bis((tert-butyldimethylsilyl)oxy)propyl)-4-methoxy-3-((phenylsulfonyl)methyl)tetrahydrofuran-2-yl)methyl)-4-methyl-5-methylenetetrahydro-2H-pyran-2-yl) ethyl)-4-methylenetetrahydrofuran-2-yl)propyl pivalate 
• 784194-08-7 (R)-2-bromo-7-(tert-butyldiphenylsilanyloxy)-hept-1-en-4-ol 
• 871355-80-5 toluene-4-sulfonic acid 3-bromo-1-[3-(tert-butyl-diphenyl-silanyloxy)-propyl]-but-3-enyl ester 

Relevant academic research and scientific papers

New catalytic cycle for couplings of aldehydes with organochromium reagents

(Chemical Equation Presented) A new catalytic cycle has been developed to effect all three subgroups of Cr-mediated couplings, i.e., (1) Ni/Cr-mediated alkenylation, alkynylation, and arylation, (2) Co/Cr-mediated 2-haloallylation, alkylation, and proparg

Process development of halaven: Synthesis of the C14-C35 fragment via iterative nozaki-hiyama-kishi reaction-williamson ether cyclization

Multikilogram manufacturing process of the Halaven C14-C35 fragment is described. The synthesis features convergent assembly of subunits by iterative asymmetric Ni/Cr-mediated coupling executed in fixed equipment. Georg Thieme Verlag Stuttgart - New York.

INTERMEDIATES FOR THE PREPARATION OF HALICHONDRIN B

The present invention provides macrocyclic compounds, synthesis of the same and intermediates thereto. Such compounds, and compositions thereof, are useful for treating or preventing proliferative disorders Formula (F-4).

Fe/Cr- and Co/Cr-mediated catalytic asymmetric 2-haloallylations of aldehydes

The first example to couple aldehydes and 3-bromo-2-halopropenes in a catalytic asymmetric manner is reported. The coupling reaction is effected by the use of a chiral sulfonamide-Cr complex (prepared in situ from 1d, CrBr3, Fe(III) or from Co(II), Et3N, and Mn), TMSCl, and 2,6-lutidine. The method reported here is operationally simple and scalable, furnishing 3-halohomoallylic alcohols with a synthetically useful level of enantiomeric excess. Copyright