871502-87-3

Basic information

• Product Name: 4-BROMO-2-FORMYLBENZOIC ACID
• Synonyms: 4-BROMO-2-FORMYLBENZOIC ACID
• CAS NO: 871502-87-3
• Molecular Formula: C₈H₅BrO₃
• Molecular Weight: 229.0275
• EINECS: -0
• Mol File: 871502-87-3.mol
• Article Data: 17

Chemical Properties

• Boiling Point: 360.6±32.0 °C(Predicted)
• Appearance: /
• Density: 1.764±0.06 g/cm3(Predicted)
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• PKA: 4.34±0.10(Predicted)
• CAS DataBase Reference: 4-BROMO-2-FORMYLBENZOIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 4-BROMO-2-FORMYLBENZOIC ACID(871502-87-3)
• EPA Substance Registry System: 4-BROMO-2-FORMYLBENZOIC ACID(871502-87-3)

Safety Data

• Hazardous Substances Data: 871502-87-3(Hazardous Substances Data)

Usage

General Description

4-Bromo-2-formylbenzoic acid is a chemical compound with the molecular formula C8H5BrO3. It is a white to light yellow crystalline powder that is sparingly soluble in water and soluble in organic solvents. 4-BROMO-2-FORMYLBENZOIC ACID is commonly used in organic synthesis and pharmaceutical research as a building block for the synthesis of various derivatives and analogs. It is also used as an intermediate in the production of dyes, pigments, and other organic compounds. As a formylbenzoic acid derivative, it has potential applications in the development of new drugs and chemotherapeutic agents due to its structural and functional properties. Additionally, it is an important chemical for the research and development of new materials and chemical processes.

Upstream product

• 670256-21-0 4-bromo-2-(hydroxymethyl)benzoic acid 
• 6941-75-9 5-Bromoisoindoline-1,3-dione 
• 65399-05-5 5-amino-3H-isobenzofuran-1-one 
• 64169-34-2 5-bromophthalide 
• 102126-70-5 5-bromo-3-bromo-3H-isobenzofuran-1-one 
• 119-67-5 o-carboxybenzaldehyde 

Downstream Products

• 1260795-42-3 methyl 4-bromo-2-formylbenzoate 
• 871502-90-8 4-bromo-2-bis(5-methyl-2-furyl)methylbenzoic acid 
• 1221485-88-6 2-(2,4-difluorophenylamino)-7-(3-hydroxy-propoxy)-10,11-dihydro-dibenzo[a,d]-cyclohepten-5-one 

Relevant articles and documents

Design, synthesis, and structure–activity relationship study of potent mapk11 inhibitors

Huntington’s disease (HD) is a rare single-gene neurodegenerative disease, which can only be treated symptomatically. Currently, there are no approved drugs for HD on the market. Studies have found that MAPK11 can serve as a potential therapeutic target f

Indium-Catalyzed C?F Bond Transformation through Oxymetalation/β-Fluorine Elimination to Access Fluorinated Isocoumarins

Fluorinated heterocycles have attracted much attention in the pharmaceutical and agrochemical industries. Many strategies have already been developed to achieve the synthesis of fluorinated heterocycles. Formidable challenges remain, however, in the synthesis of fluorinated isocoumarin derivatives that are among the most alluring structural motifs. Herein, the indium-catalyzed C?F bond transformation of 2-(2,2-difluorovinyl) benzoates is reported, which are readily accessible compounds, to give a diverse array of fluorinated isocoumarins. The present reaction proceeds smoothly using inexpensive reagents: a catalytic amount of indium salt in the presence of zinc salt. A theoretical calculation of potential energy profiles showed that the reaction consists of oxymetalation with the elimination of alkyl halide and the β-fluorine elimination.

Bioorthogonal double-fluorogenic siliconrhodamine probes for intracellular super-resolution microscopy

A series of double-fluorogenic siliconrhodamine probes were synthesized. These tetrazine-functionalized, membrane-permeable labels allowed site-specific bioorthogonal tagging of genetically manipulated intracellular proteins and subsequent imaging using s