871566-23-3

Upstream product

• 871566-09-5 [((4R,5R)-4-Hydroxy-5-methoxy-4,5-dihydro-furan-2-carbonyl)-amino]-acetic acid benzyl ester 
• 1738-68-7 Gly-OBz 
• 63104-97-2 (E)-4-(4-nitrophenyl)-4-oxobut-2-enoic acid 
• 54837-33-1 methyl (methyl-3-deoxy-β-D-glycero-pent-3-enofuranoside)uronate 

Downstream Products

• 871566-25-5 {[(2R,2aR,4aR,6R,7aS,7bS)-6-(4-Amino-phenyl)-2-methoxy-4-oxo-hexahydro-1,3,7-trioxa-cyclopenta[cd]indene-7a-carbonyl]-amino}-acetic acid 

Relevant academic research and scientific papers

Transformation of D-(-)-ribose into a natural product-like scaffold via a Lewis acid catalyzed intramolecular hetero-diels-alder reaction

Starting from D-(-)-ribose, a tricyclic natural product-like scaffold suitable for combinatorial derivatization was synthesized via an intramolecular hetero-Diels-Alder reaction. Lithium perchlorate was found to enhance the reaction rate and, at the same time, had a pronounced influence on the chemoselectivity of the reaction. The stereochemical course of the reaction, however, was not influenced by the Lewis acid. Copyright Taylor & Francis Group, LLC.

Solid-support synthesis of natural product-like compounds derived from D-(-)-ribose

The synthesis of natural product-like compounds on solid support is described. Starting from a readily accessible D-(-)-ribose derivative, a tricyclic scaffold is prepared in five steps. After coupling onto solid supports bearing different substituents (P