871570-99-9Relevant academic research and scientific papers
Palladium mediated synthesis of isoindolinones and isoquinolinones
Wahab Khan,Masud Reza
, p. 11204 - 11210 (2007/10/03)
The palladium-catalyzed reactions of 2-iodo-N-substituted benzamides 5-10 with acrylic esters 11-14 led to N-substituted-3-alkylisoindolinone esters 15-22 in good yields. The esters of isoindolinones 15-22 underwent hydrolysis reactions yielding the N-aryl-1,2,3,4-tetrahydro-1-oxoisoquinoline-3-carboxylic acid 26-31 in good yields.
