871735-70-5Relevant academic research and scientific papers
A stereospecific synthesis of both enantiomers of 2-(1'-amino-2'-methylpropyl)imidazole, a key synthon in the synthesis of SB 203386; a potent protease inhibitor
Pridgen, Lendon N.,Mokhallalati, Mohamed K.,McGuire, Michael A.
, p. 1275 - 1278 (1997)
Two methods for the asymmetric synthesis of both enantiomers of 2-(1'-amino-2'-methylpropyl)imidazole (2) have been developed by adding nucleophilic organometallics to nonracemic 2-oxazolidinones employing 2-phenylglycinol as the source of chirality. Exce
