871819-53-3

Basic information

• Product Name: 4-(3-chloro-phenylamino)-1-methyl-1H-pyrrolo[3,2-c]pyridine-7-carboxylic acid methyl ester
• Synonyms: 4-(3-chloro-phenylamino)-1-methyl-1H-pyrrolo[3,2-c]pyridine-7-carboxylic acid methyl ester
• CAS NO: 871819-53-3
• Molecular Weight: 315.759
• Mol File: 871819-53-3.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 4-(3-chloro-phenylamino)-1-methyl-1H-pyrrolo[3,2-c]pyridine-7-carboxylic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(3-chloro-phenylamino)-1-methyl-1H-pyrrolo[3,2-c]pyridine-7-carboxylic acid methyl ester(871819-53-3)
• EPA Substance Registry System: 4-(3-chloro-phenylamino)-1-methyl-1H-pyrrolo[3,2-c]pyridine-7-carboxylic acid methyl ester(871819-53-3)

Safety Data

• Hazardous Substances Data: 871819-53-3(Hazardous Substances Data)

Upstream product

• 871819-41-9 methyl 2-{(Z)-2-amino-1-[(rnethyloxy)carbonyl]ethenyl}-1-methyl-1H-pyrrole-3-carboxylate 
• 871819-40-8 2-(2-hydroxy-1-methoxycarbonyl-vinyl)-1-methyl-1H-pyrrole-3-carboxylic acid methyl ester 
• 925917-48-2 2-(2-amino-1-methoxycarbonyl-vinyl)-1-methyl-1H-pyrrole-3-carboxylic acid methyl ester 
• 871819-42-0 1-methyl-4-oxo-4,5-dihydro-1H-pyrrolo[3,2-c]pyridine-7-carboxylic acid methyl ester 
• 871819-43-1 4-chloro-1-methyl-1H-pyrrolo[3,2-c]pyridine-7-carboxylic acid methyl ester 
• 108-42-9 3-chloro-aniline 

Downstream Products

• 871819-38-4 4-(3-chloro-phenylamino)-1-methyl-1H-pyrrolo[3,2-c]pyridine-7-carboxylic acid 

Relevant articles and documents

Discovery of 1-[4-(3-chlorophenylamino)-1-methyl-1H-pyrrolo[3,2-c]pyridin- 7-yl]-1-morpholin-4-ylmethanone (GSK554418A), a brain penetrant 5-azaindole CB2 agonist for the treatment of chronic pain

We report the synthesis and SAR of a series of novel azaindole CB 2 agonists. 6-Azaindole 18 showed activity in an acute pain model but was inactive in a chronic model. 18 is a Pgp substrate with low brain penetration. The template was redesign