872-30-0

Basic information

• Product Name: (2-Methyloxiran-2-yl)Methanol
• Synonyms: 2-MethyloxiraneMethanol;(2-Methyloxiran-2-yl)Methanol
• CAS NO: 872-30-0
• Molecular Formula: C₄H₈O₂
• Molecular Weight: 88.10512
• Mol File: 872-30-0.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 141.8°Cat760mmHg
• Flash Point: 62.8°C
• Appearance: /
• Density: 1.084g/cm³
• PKA: 14.44±0.10(Predicted)
• CAS DataBase Reference: (2-Methyloxiran-2-yl)Methanol(CAS DataBase Reference)
• NIST Chemistry Reference: (2-Methyloxiran-2-yl)Methanol(872-30-0)
• EPA Substance Registry System: (2-Methyloxiran-2-yl)Methanol(872-30-0)

Safety Data

• Hazardous Substances Data: 872-30-0(Hazardous Substances Data)

Usage

General Description

(2-Methyloxiran-2-yl)Methanol, also known as 2,2-Dimethyloxirane-2-methanol, is a chemical compound with the molecular formula C5H10O2. It is a colorless liquid with a slightly sweet odor, and it is commonly used as a chemical intermediate in the production of various products such as pharmaceuticals, pesticides, and fragrances. It is also used as a solvent for cellulose esters and ethers, and as a stabilizer for plastics and resins. Additionally, (2-Methyloxiran-2-yl)Methanol is used in the synthesis of epoxy resins and as a reagent in organic synthesis. It is important to handle this compound with care, as it may cause irritation to the skin, eyes, and respiratory system, and it should be stored in a cool, well-ventilated area away from sources of ignition.

Upstream product

• 513-42-8 3-hydroxy-2-methyl-1-propene 
• 67872-66-6 α-methyl-α-((1-tert-butoxy-2-methyl-2,3-epoxypropyl)oxy)-β-propiolactone 

Downstream Products

• 86884-90-4 (S)-2-methylglycidol 
• 60285-43-0 Acetic acid (S)-2-methyl-oxiranylmethyl ester 
• 138806-47-0 (+/-)-2-Methyl-1-(tosyloxy)-2,3-epoxypropan 
• 25245-58-3 2-methylpropane-1,2,3-triol 
• 86884-89-1 (R)-2-methylglycidol 
• 1609085-76-8 2-methyl-3-(phenylamino)propane-1,2-diol 
• 592-20-1 Acetol acetate 
• 106268-96-6 (2R)-methyl-3-[4-nitrobenzoyl(oxy)]-1,2-epoxy-propane 
• 118200-96-7 (2S)-methyl-3-[4-nitrobenzoyl(oxy)]-1,2-epoxy-propane 

Relevant articles and documents

Olefin epoxidation with hydrogen peroxide catalyzed by lacunary polyoxometalate [γ-SiW10O34(H2O) 2]4-

The tetra-n-butylammonium (TBA) salt of the divacant Keggin-type polyoxometalate [TBA]4[γ-SiW10O34-(H 2O)2] (I) catalyzes the oxygen-transfer reactions of olefins, allylic alcohols, and sulfides with 30% aqueous hydrogen peroxide. The negative Hammett ρ+ (-0.99) for the competitive oxidation of p-substituted styrenes and the low value of (nucleophilic oxidation)/(total oxidation), Xso = 0.04, for I-catalyzed oxidation of thianthrene 5-oxide (SSO) reveals that a strongly electrophilic oxidant species is formed on I. The preferential formation of trans-spoxide during epoxidation of 3-methyl-1-cyclohexene demonstrates the steric constraints of the active site of I. The I-catalyzed epoxidation proceeds with an induction period that disappears upon treatment of I with hydrogen peroxide. 29Si and 183W NMR spectroscopy and CSI mass spectrometry show that reaction of I with excess hydrogen peroxide leads to fast formation of a diperoxo species, [TBA]4[γ-SiW10O32(O2) 2] (II), with retention of a γ-Keggin type structure. Whereas the isolated compound II is inactive for stoichiometric epoxidation of cyclooctene, epoxidation with II does proceed in the presence of hydrogen peroxide. The reaction of II with hydrogen peroxide would form a reactive species (III), and this step corresponds to the induction period observed in the catalytic epoxidation. The steric and electronic characters of III are the same as those for the catalytic epoxidation by I. Kinetic, spectroscopic, and mechanistic investigations show that the present epoxidation proceeds via III.